绿色合成及新型唑类化合物的抗菌活性评价
Green synthesis and biological evaluation of some novel azoles as antimicrobial agents.
机构信息
Department of Chemistry, SSGM College, Kopargaon, Dist-Ahmednagar (MH), India.
出版信息
Bioorg Med Chem Lett. 2010 Dec 15;20(24):7200-4. doi: 10.1016/j.bmcl.2010.10.111. Epub 2010 Oct 27.
PMID:21074427
Abstract
A series of novel fluorine-containing triazoles 3, thiadiazoles 4, and oxadiazoles 5 were synthesized from thiosemicarbazides 2. These reactions were carried out by green technique such as ultrasonication and microwave. All products have been characterized by IR, (1)H NMR, and Mass spectral study and screened for their antimicrobial activity.
摘要
一系列新型含氟三唑 3、噻二唑 4 和恶二唑 5 是由硫代氨基脲 2 合成的。这些反应是通过超声和微波等绿色技术进行的。所有产物均通过红外光谱 (IR)、(1)H NMR 和质谱研究进行了表征，并对其进行了抗菌活性筛选。
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