Department of Neurology, Children's University Hospital, Temple Street, Dublin 7, Ireland.
Eur J Paediatr Neurol. 2011 Mar;15(2):91-4. doi: 10.1016/j.ejpn.2010.10.002. Epub 2010 Nov 11.
Posterior Reversible Encephalopathy Syndrome (PRES) is a clinicoradiologic syndrome characterised clinically by headaches, altered consciousness, visual disturbances and seizures and radiological changes which can resolve. However left untreated it can be fatal and not all cases are reversible. It can occur in many settings, the most common being hypertensive crisis. We discuss the clinical and radiological features of this increasingly diagnosed condition among children and current thinking on its pathogenesis. A brief case is used to highlight the variable presentation of PRES. PRES is often unsuspected by the clinician and radiologists may be first to suggest the diagnosis. Accurate assessment including blood pressure measurement, appropriate imaging and rapid treatment is required to avoid a devastating outcome.
后部可逆性脑病综合征 (PRES) 是一种临床影像学综合征，其临床特征为头痛、意识改变、视觉障碍和癫痫发作以及可消退的影像学改变。然而，如果不加以治疗，它可能是致命的，并非所有病例都是可逆的。它可以发生在许多情况下，最常见的是高血压危象。我们讨论了儿童中这种越来越常见的疾病的临床和影像学特征以及目前对其发病机制的认识。一个简要的病例用于突出 PRES 的多变表现。PRES 通常不为临床医生所怀疑，放射科医生可能是第一个提出诊断的人。需要进行准确的评估，包括血压测量、适当的影像学检查和快速治疗，以避免灾难性的结果。
