重症肺炎合并多器官功能衰竭时T细胞隐蔽抗原（TCA）激活

T-cryptantigen (TCA) activation in sever pneumonia complicated with multiple organ failure.

作者信息

Wang Qiushi, Liu Delong, Bai Yingzhe

机构信息

Department of Blood Transfusion, Shengjing Hospital, China Medical University, Shenyang 110004, China.

出版信息

Transfus Apher Sci. 2010 Dec;43(3):361-364. doi: 10.1016/j.transci.2010.10.008. Epub 2010 Nov 13.

DOI:10.1016/j.transci.2010.10.008

PMID:21075688

Abstract

A 19-month-old boy presented RBC T-cryptantigen (TCA) activation with severe pneumonia complicated with abnormal coagulation. The boy received fresh frozen plasma before TCA activation was confirmed. He developed hemolysis and multiple organ failure. The hemolysis anemia was successfully treated with washed RBC transfusion. However, he had to use dialysis because of renal dysfunction. The case prompted an urgent call to screen RBC TCA-activation in selective pediatric patients.

摘要

一名19个月大的男孩出现红细胞T隐抗原（TCA）激活，伴有严重肺炎并合并凝血异常。该男孩在TCA激活得到确认之前接受了新鲜冰冻血浆。他出现了溶血和多器官功能衰竭。通过输注洗涤红细胞成功治疗了溶血性贫血。然而，由于肾功能不全，他不得不接受透析治疗。该病例促使人们紧急呼吁对部分儿科患者进行红细胞TCA激活筛查。