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端粒缩短是衰老与2型糖尿病流行之间缺失的环节吗?

Is shortening of telomeres the missing link between aging and the Type 2 Diabetes epidemic?

作者信息

Mulder Hindrik

机构信息

Department of Experimental Medical Science, Lund, Sweden.

出版信息

Aging (Albany NY). 2010 Oct;2(10):634-6. doi: 10.18632/aging.100224.

Abstract

The world is facing an impending epidemic of diabetes [1]. Diabetes occurs in two forms - Type 1 and Type 2. These are separate entities, although they share an elevation of fasting plasma glucose (≥7.0 mM or 126 mg/dl) as the only required diagnostic criterion. The diabetes epidemic can be attributed to Type 2 Diabetes. Historically, Type 2 Diabetes has been a disease of the aged population. Recently, a drift in the incidence is observed, with younger individuals developing Type 2 Diabetes.

摘要

世界正面临一场迫在眉睫的糖尿病流行[1]。糖尿病有两种类型——1型和2型。尽管它们都以空腹血糖升高(≥7.0毫摩尔/升或126毫克/分升)作为唯一必要的诊断标准,但这两种类型是不同的疾病。糖尿病流行可归因于2型糖尿病。从历史上看,2型糖尿病一直是老年人群的疾病。最近,观察到发病率出现了变化,越来越多的年轻人患上了2型糖尿病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75fe/2993791/b150d294ee8c/aging-02-634-g001.jpg

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