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运用荟萃分析来估计出生体重与出生时其他人体测量指标之间的相关系数。

Meta-analysis to estimate the correlation coefficients between birthweight and other anthropometric measurements at birth.

机构信息

Department of Medicine and Public Health, Mizawa Hospital, 3-3-1, Sato Naka-ku, Hamamatsu, 430-0807, Japan.

出版信息

Indian J Pediatr. 2011 Mar;78(3):311-8. doi: 10.1007/s12098-010-0288-6. Epub 2010 Nov 14.

Abstract

OBJECTIVE

To pool the correlation coefficients between birthweight (BW) and other newborn anthropometric measurements at birth.

METHODS

Meta-analysis, using a random-effects model. Any study, published in the English language, showing the correlation coefficients between BW and other anthropometric measurements of living neonates at birth was eligible. The Z- scores, transformed from the correlation coefficients were pooled, and afterwards they were back transformed to the pooled correlation coefficients.

RESULTS

The correlations of BW with (mid upper-) arm circumference (MUAC) and chest circumference (CHC) were frequently studied (n, 76 and 71; pooled correlation coefficient, 0.81 and 0.84; 95%CI, 0.78-0.84 and 0.82-0.86). The Z- scores of the pooled correlation coefficient between BW vs. CHC, the highest among the correlation coefficients of BW, was not substantially different from the Z- scores between BW vs. calf circumference (CC), thigh circumference (TC), MUAC, or abdominal circumference (AC) (p, 0.889, 0.351, 0.076, and 0.053, respectively), but the study numbers of CC, TC, or AC were remarkably low (n, 13, 19, and 6, respectively) compared with CHC or MUAC.

CONCLUSIONS

CHC and MUAC may be among the most promising candidates as the surrogates of BW, based on the study numbers, and the level of pooled correlation coefficients.

摘要

目的

汇总出生体重 (BW) 与出生时其他新生儿人体测量学指标的相关系数。

方法

使用随机效应模型进行荟萃分析。符合条件的研究为发表在英文期刊上、显示 BW 与出生时活产儿其他人体测量学指标之间相关系数的研究。将相关系数转化为 Z 分数进行汇总,然后反转为汇总相关系数。

结果

BW 与(中上臂)臂围 (MUAC) 和胸围 (CHC) 的相关性经常被研究(n=76 和 71;汇总相关系数分别为 0.81 和 0.84;95%CI 分别为 0.78-0.84 和 0.82-0.86)。BW 与 CHC 之间的汇总相关系数的 Z 分数是 BW 相关系数中最高的,与 BW 与小腿围 (CC)、大腿围 (TC)、MUAC 或腹围 (AC) 之间的 Z 分数无显著差异(p 分别为 0.889、0.351、0.076 和 0.053),但 CC、TC 或 AC 的研究数量明显较少(n 分别为 13、19 和 6)。

结论

基于研究数量和汇总相关系数的水平,CHC 和 MUAC 可能是 BW 最有前途的替代指标。

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