Braun F, Wilhelm H
Augenklinik, Katharinenhospital Stuttgart.
Klin Monbl Augenheilkd. 2010 Nov;227(11):852-6. doi: 10.1055/s-0029-1245846. Epub 2010 Nov 12.
Colour comparison tests are a subjective supplement to the swinging flashlight test. We have investigated the specificity and sensitivity, compared 3 exactly defined different colours (red, green, blue), and looked for age relationships.
101 patient with various unilateral optic neuropathies were compared to 103 age-correlated healthy controls in randomised order by letting the patient evaluate red, green and blue colour charts of 5.5 cm diameter.
The area under the receiver operator characteristics curve was 0.804 for red, 0.821 for green and 0.789 for blue, and for any of the 3 colours 0.835 (at least one colour was seen differently). Best results were obtained when even small differences in colour perception were considered as pathological. 29 healthy controls perceived colours differently in both eyes, 24 of those being older than 50 years. The specificity decreased with age, was significant for green and red, not for blue.
There were no significant differences between the 3 colours in all age groups. Evaluation of more than one colour does not increase the sensitivity significantly. Even small differences have to be considered as pathological to obtain the highest possible sensitivity. Test specifity decreases with age.
颜色对比测试是对摆动手电筒试验的一种主观补充。我们研究了其特异性和敏感性，比较了三种精确界定的不同颜色（红色、绿色、蓝色），并探寻了年龄关系。
通过让101例患有各种单侧视神经病变的患者对直径5.5厘米的红色、绿色和蓝色色卡进行评估，以随机顺序将他们与103名年龄匹配的健康对照者进行比较。
红色的受试者工作特征曲线下面积为0.804，绿色为0.821，蓝色为0.789，三种颜色中任一种的曲线下面积为0.835（至少有一种颜色的感知不同）。当将颜色感知上的微小差异也视为病理性差异时，可获得最佳结果。29名健康对照者双眼颜色感知不同，其中24人年龄超过50岁。特异性随年龄降低，绿色和红色有显著变化，蓝色则无。
在所有年龄组中，三种颜色之间无显著差异。评估一种以上颜色并不会显著提高敏感性。为获得尽可能高的敏感性，即使微小差异也必须视为病理性差异。测试特异性随年龄降低。
