Department of Mathematics and Computer Science, Hobart and William Smith Colleges, Geneva, NY 14456, United States.
Math Biosci Eng. 2010 Oct;7(4):765-77. doi: 10.3934/mbe.2010.7.765.
Mathematical models have been used to study the dynamic interaction of many infectious diseases with the host's immune system. In this paper, we study Varicella Zoster Virus, which is responsible for chicken pox (varicella), and after a long period of latency, herpes zoster (shingles). After developing the model and demonstrating that is exhibits the type of periodic behavior necessary for long term latency and reactivation, we examine the implications of the model for vaccine booster programs aimed at preventing herpes zoster.
数学模型已被用于研究许多传染病与宿主免疫系统的动态相互作用。在本文中，我们研究了导致水痘（带状疱疹）的水痘带状疱疹病毒，以及在长期潜伏期后出现的带状疱疹（带状疱疹）。在开发模型并证明其表现出必要的周期性行为类型以实现长期潜伏期和再激活后，我们研究了该模型对旨在预防带状疱疹的疫苗加强计划的影响。
