Department of Neurology, University Hospitals Case Medical Center, Cleveland, Ohio, USA.
Epileptic Disord. 2010 Dec;12(4):335-7. doi: 10.1684/epd.2010.0343. Epub 2010 Nov 16.
Rare cases of levetiracetam-induced thrombocytopenia have been reported in the literature. We report a case of glioblastoma multiforme and partial epilepsy treated with levetiracetam with subsequent development of thrombocytopenia. After ruling out all other possible causes of a decreased platelet count, we conclude that levetiracetam was the cause of this adverse event.
文献中报道了罕见的左乙拉西坦诱导的血小板减少症病例。我们报告了一例多形性胶质母细胞瘤和部分性癫痫患者使用左乙拉西坦治疗后发生血小板减少症的病例。在排除了血小板计数降低的所有其他可能原因后,我们得出结论,左乙拉西坦是导致这一不良事件的原因。