Program in Molecular Medicine, University of Utah, Salt Lake City, UT 84112, USA.
J Cell Biol. 2010 Nov 15;191(4):699-700. doi: 10.1083/jcb.201010082.
In this issue, Thon et al. (2010. J. Cell Biol. doi: 10.1083/jcb.201006102) demonstrate that newly released platelets exhibit bipolar behavior, shifting back and forth between round cells and multibodied proplatelets (Thon et al., 2010). The authors define this intermediate as a preplatelet and, in doing so, shed new insight into the terminal steps of platelet maturation.
在本期中,Thon 等人(2010. J. Cell Biol. doi: 10.1083/jcb.201006102)证明新释放的血小板表现出双极行为,在圆形细胞和多体伸片之间来回转换(Thon 等人,2010)。作者将这个中间阶段定义为前血小板,从而为血小板成熟的最后阶段提供了新的见解。