Mallarini G, Saba L
Department of Radiology, University Hospital of Cagliari - Monserrato, Cagliari, Italy.
Minerva Ginecol. 2010 Dec;62(6):541-9.
The prevalence of infertility in the United States is 15-20% and this condition represents an important medical problem. The purpose of this work was to evaluate therapeutical efficacy of 2 consecutive hysterosalpingography (HSG) followed each other after 4 week compared with the fallopian tube recanalization (FTR).
Two groups of 80 patients paired for mean age and age range (age range, 23-37 years; mean age, 30 years), were assessed for pregnancy rate (two-year follow-up) by using two consecutive HSG in one group and HSG and tube recanalization in the second group. Pain perception and dose delivered were assessed. Statistical analysis was performed to evaluate significant differences between the two approaches.
Pregnancy rate after TFR was 51% whereas pregnancy rate after two consecutive HSG was 31.3% (P= 0.016; OR 2.31) and all the pregnancies were observed in those women that showed a positive variation in second HSG with a pregnancy rate of 47% (P=0.776; OR=1.18). In one case a serious complication was observed (1.25%): a tubal perforation. Minor bleeding sometimes lasted for as long as 48 h but never required any medical treatment. Pain assessment and dose delivered were statistically different by using these two methods (P= 0.027 and P<0.001, respectively)
Therapeutical efficacy of two consecutive HSG followed each other after four week compared with the FTR are similar when the second HSG shows the presence of Fallopian tube patency.
在美国,不孕症的患病率为15%-20%,这一情况是一个重要的医学问题。本研究的目的是评估连续两次子宫输卵管造影术(HSG)在4周后相继进行与输卵管再通术(FTR)相比的治疗效果。
两组各80例患者,根据平均年龄和年龄范围(年龄范围23-37岁;平均年龄30岁)进行配对,一组通过连续两次HSG评估妊娠率(两年随访),另一组通过HSG和输卵管再通术评估妊娠率。评估疼痛感知和给予的剂量。进行统计分析以评估两种方法之间的显著差异。
输卵管再通术后的妊娠率为51%,而连续两次HSG后的妊娠率为31.3%(P=0.016;OR=2.31),所有妊娠均出现在第二次HSG显示阳性变化的女性中,妊娠率为47%(P=0.776;OR=1.18)。观察到1例严重并发症(1.25%):输卵管穿孔。轻微出血有时持续长达48小时,但从未需要任何治疗。使用这两种方法时,疼痛评估和给予的剂量在统计学上存在差异(分别为P=0.027和P<0.001)。
当第二次HSG显示输卵管通畅时,连续两次HSG在4周后相继进行与输卵管再通术相比,治疗效果相似。