Georgetown University, Department of Emergency Medicine, Washington, DC.
West J Emerg Med. 2010 Sep;11(4):354-7.
In 1996 Sgarbossa reviewed 17 ventricular-paced electrocardiograms (ECGs) in acute myocardial infarction (AMI) for signs of ischemia. Several characteristics of the paced ECG were predictive of AMI. We sought to evaluate the criteria in ventricular-paced ECGs in an emergency department (ED) cohort.
Ventricular-paced ECGs in patients with elevated cardiac markers within 12 hours of the ED ECG and a diagnosis of AMI were identified retrospectively (n=57) and compared with a control group of patients with ventricular-paced ECGs and negative cardiac markers (n=99). A blinded board certified cardiologist reviewed all ECGs for Sgarbossa criteria. This study was approved by the institutional review board.
Application of Sgarbossa's criteria to the paced ECGs revealed the following: The sensitivity of "ST-segment elevation of 1 mm concordant with the QRS complex" was unable to be calculated as no ECG fit this criterion;For "ST-segment depression of 1 mm in lead V1, V2, or V3," the sensitivity was 19% (95% CI 11-31%), specificity 81% (95% CI 72-87%), with a likelihood ratio of 1.06 (0.63-1.64);For "ST-segment elevation >5mm discordant with the QRS complex," the sensitivity was 10% (95% CI 5-21%), specificity 99% (95% CI 93-99%), with a likelihood ratio of 5.2 (1.3 - 21).
In our review of ventricular-paced ECGs, the most clinically useful Sgarbossa criterion in identifying AMI was ST-segment elevation >5mm discordant with the QRS complex. This characteristic may prove helpful in identifying patients who may ultimately benefit from early aggressive AMI treatment strategies.
1996 年,Sgarbossa 教授在急性心肌梗死(AMI)患者中回顾性分析了 17 份心室起搏心电图(ECG),以寻找缺血的迹象。起搏 ECG 的几个特征对 AMI 具有预测价值。我们试图在急诊科(ED)队列中评估起搏 ECG 的标准。
回顾性分析了在 ED 心电图 12 小时内心脏标志物升高且诊断为 AMI 的患者的心室起搏 ECG(n=57),并与心室起搏 ECG 且心脏标志物阴性的患者对照组(n=99)进行比较。一位经过盲法认证的心脏病专家对所有 ECG 进行了 Sgarbossa 标准的审查。本研究获得了机构审查委员会的批准。
将 Sgarbossa 标准应用于起搏 ECG 显示如下:“与 QRS 波群一致的 1mm ST 段抬高”的敏感性无法计算,因为没有 ECG 符合此标准;对于“V1、V2 或 V3 导联 1mm 的 ST 段压低”,敏感性为 19%(95%CI 11-31%),特异性为 81%(95%CI 72-87%),似然比为 1.06(0.63-1.64);对于“与 QRS 波群不一致的 ST 段抬高>5mm”,敏感性为 10%(95%CI 5-21%),特异性为 99%(95%CI 93-99%),似然比为 5.2(1.3-21)。
在我们对心室起搏 ECG 的回顾中,最具临床意义的 Sgarbossa 标准是与 QRS 波群不一致的 ST 段抬高>5mm,这一特征可能有助于识别最终可能从积极的 AMI 治疗策略中获益的患者。