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[影像学失语症]

[Imaging aphasia].

作者信息

Saur D

机构信息

Klinik und Poliklinik für Neurologie, Universitätsklinikum, Liebigstraße 20, 04103, Leipzig.

出版信息

Nervenarzt. 2010 Dec;81(12):1429-37. doi: 10.1007/s00115-010-3106-5.

Abstract

Language is organized in a left-lateralized temporo-frontal network. This network organization enables the brain to reorganize language functions to compensate the deficit after focal brain damage, e.g. ischemic stroke. Clinically, we often observe a high functional dynamic in language performance within the first few days after stroke with a slower improvement in the further course. This suggests that distinct neuronal mechanisms contribute to the functional improvement during the different phases. This article describes how structural and functional MRI methods contribute to understanding loss and recovery of language functions after stroke. In addition, the method of pattern recognition techniques is introduced to demonstrate how language recovery can be predicted from early language fMRI data.

摘要

语言由左侧颞叶-额叶网络组织而成。这种网络组织使大脑能够重新组织语言功能,以补偿局灶性脑损伤(如缺血性中风)后的功能缺陷。临床上,我们经常观察到中风后的头几天内语言表现具有高度的功能动态变化,而在后续过程中改善较慢。这表明不同的神经元机制在不同阶段促成了功能改善。本文描述了结构和功能磁共振成像方法如何有助于理解中风后语言功能的丧失和恢复。此外,还介绍了模式识别技术方法,以展示如何从早期语言功能磁共振成像数据预测语言恢复情况。

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