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癫痫患儿的学习障碍

Learning disorders in children with epilepsy.

作者信息

Pavlou Evangelos, Gkampeta Anastasia

机构信息

2nd Department of Pediatrics, Aristotle University of Thessaloniki, AHEPA General Hospital, Elaiones Pilaias, Thessaloniki 55535, Greece.

出版信息

Childs Nerv Syst. 2011 Mar;27(3):373-9. doi: 10.1007/s00381-010-1321-9. Epub 2010 Nov 16.

DOI:10.1007/s00381-010-1321-9
PMID:21080176
Abstract

INTRODUCTION

Learning Disorders (LD) are defined as disorders that interfere with academic performance or with daily activities that require reading, writing or mathematical skills in subjects with a normal intelligence quotient (IQ). The prevalence of LD in the general population has been found to be 2-10%, and reading disorders are the most frequent subtype. Epilepsy is one of the most common serious neurological disorders in childhood. LD are more common in children with epilepsy than in the general population. As a consequence, the risk of cognitive impairment in children with epilepsy is high, and a review of the literature needs to be fully presented.

METHODS

Narrative review including articles regarding LD in children with various epileptic syndromes published in the international medical literature.

RESULTS

LD are more frequent among children with epilepsy. The etiology is multifactorial, being affected by the type of epileptic syndrome, the age of onset and the antiepileptic treatment being selected. LD can be either permanent or state-dependent. Each category has different treatment protocols and prognosis.

CONCLUSIONS

Despite the fact that the findings of the studies discussed in our article support the evidence that epilepsy in childhood impairs the cognitive function, we should not underestimate the role of demographic and psychosocial factors on academic performance of children with epilepsy. Despite the high prevalence of LD, a healthy family and school environment can help reduce its impact on the patient's quality of life.

摘要

引言

学习障碍(LD)被定义为干扰学业成绩或干扰那些在智商(IQ)正常的情况下需要阅读、写作或数学技能的日常活动的障碍。在普通人群中,学习障碍的患病率为2%-10%,阅读障碍是最常见的亚型。癫痫是儿童期最常见的严重神经系统疾病之一。学习障碍在癫痫患儿中比在普通人群中更常见。因此,癫痫患儿出现认知障碍的风险很高,需要全面呈现对相关文献的综述。

方法

叙述性综述,包括国际医学文献中发表的关于各种癫痫综合征患儿学习障碍的文章。

结果

学习障碍在癫痫患儿中更为常见。病因是多因素的,受癫痫综合征类型、发病年龄和所选抗癫痫治疗的影响。学习障碍可以是永久性的或状态依赖性的。每一类都有不同的治疗方案和预后。

结论

尽管我们文章中讨论的研究结果支持儿童癫痫会损害认知功能这一证据,但我们不应低估人口统计学和社会心理因素对癫痫患儿学业成绩的作用。尽管学习障碍患病率很高,但健康的家庭和学校环境有助于减轻其对患者生活质量的影响。

相似文献

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Learning disorders in children with epilepsy.癫痫患儿的学习障碍
Childs Nerv Syst. 2011 Mar;27(3):373-9. doi: 10.1007/s00381-010-1321-9. Epub 2010 Nov 16.
2
Learning disorders in epilepsy.癫痫中的学习障碍。
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Intelligence quotient (IQ) among children with epilepsy: National epidemiological study - Sudan.儿童癫痫的智商:全国流行病学研究-苏丹。
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Learning disabilities.学习障碍
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Poor School Academic Performance and Benign Epilepsy with Centro-Temporal Spikes.学业成绩不佳与中央颞区棘波良性癫痫
Behav Sci (Basel). 2023 Jan 28;13(2):106. doi: 10.3390/bs13020106.
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Effect of cognitive behavioral intervention on anxiety, depression, and quality of life in patients with epilepsy.认知行为干预对癫痫患者焦虑、抑郁及生活质量的影响。

本文引用的文献

1
Epilepsy, learning, and behavior in childhood.儿童时期的癫痫、学习和行为。
Epilepsia. 1995;36 Suppl 1:S58-63. doi: 10.1111/j.1528-1157.1995.tb01654.x.
2
Neuropsychological status at seizure onset in children: risk factors for early cognitive deficits.儿童癫痫发作起始时的神经心理状态:早期认知缺陷的危险因素。
Neurology. 2009 Aug 18;73(7):526-34. doi: 10.1212/WNL.0b013e3181b23551. Epub 2009 Aug 12.
3
Attention-deficit disorders and epilepsy in childhood: incidence, causative relations and treatment possibilities.儿童注意力缺陷障碍与癫痫:发病率、因果关系及治疗可能性
Am J Transl Res. 2022 Jul 15;14(7):5077-5087. eCollection 2022.
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Chronic pediatric diseases and risk for reading difficulties: a narrative review with recommendations.儿童慢性疾病与阅读困难风险:综述性叙述及建议
Pediatr Res. 2022 Oct;92(4):966-978. doi: 10.1038/s41390-022-01934-y. Epub 2022 Feb 4.
5
Children with well controlled epilepsy possess different spatio-temporal patterns of causal network connectivity during a visual working memory task.癫痫得到良好控制的儿童在视觉工作记忆任务期间具有不同的因果网络连通性时空模式。
Cogn Neurodyn. 2016 Apr;10(2):99-111. doi: 10.1007/s11571-015-9373-x. Epub 2016 Jan 6.
6
Computer-assisted cognitive behavioral therapy for children with epilepsy and anxiety: a pilot study.计算机辅助认知行为疗法治疗癫痫伴发焦虑的儿童:一项初步研究。
Epilepsy Behav. 2013 Apr;27(1):70-6. doi: 10.1016/j.yebeh.2012.12.014. Epub 2013 Feb 1.
7
Disrupted functional brain connectivity in partial epilepsy: a resting-state fMRI study.部分性癫痫的功能脑连接中断:一项静息态 fMRI 研究。
PLoS One. 2011;7(1):e28196. doi: 10.1371/journal.pone.0028196. Epub 2012 Jan 5.
J Child Neurol. 2009 Jun;24(6):727-33. doi: 10.1177/0883073808330165.
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Attention deficit hyperactivity disorder in children with epilepsy.癫痫患儿的注意力缺陷多动障碍
Brain Dev. 2010 Jan;32(1):10-6. doi: 10.1016/j.braindev.2009.03.005. Epub 2009 Apr 14.
5
Patient-reported cognitive side effects of antiepileptic drugs: predictors and comparison of all commonly used antiepileptic drugs.患者报告的抗癫痫药物认知副作用:所有常用抗癫痫药物的预测因素及比较
Epilepsy Behav. 2009 Jan;14(1):202-9. doi: 10.1016/j.yebeh.2008.10.017. Epub 2008 Dec 17.
6
Childhood absence epilepsy: behavioral, cognitive, and linguistic comorbidities.儿童失神癫痫:行为、认知和语言共病
Epilepsia. 2008 Nov;49(11):1838-46. doi: 10.1111/j.1528-1167.2008.01680.x. Epub 2008 Jun 13.
7
Academic underachievement among children with epilepsy: proportion exceeding psychometric criteria for learning disability and associated risk factors.癫痫患儿学业成绩不佳:超过学习障碍心理测量标准的比例及相关风险因素。
J Learn Disabil. 2008 May-Jun;41(3):195-207. doi: 10.1177/0022219408317548.
8
Absence epilepsy in childhood: electroencephalography (EEG) does not predict outcome.儿童失神癫痫:脑电图(EEG)无法预测预后。
J Child Neurol. 2007 Jul;22(7):799-802. doi: 10.1177/0883073807304198.
9
An update on determination of language dominance in screening for epilepsy surgery: the Wada test and newer noninvasive alternatives.癫痫手术筛查中语言优势半球判定的最新进展:Wada试验及更新的非侵入性替代方法
Epilepsia. 2007 Mar;48(3):442-55. doi: 10.1111/j.1528-1167.2007.01012.x. Epub 2007 Feb 21.
10
Intellectual and language findings and their relationship to EEG characteristics in benign childhood epilepsy with centrotemporal spikes.儿童良性中央颞区棘波癫痫的智力和语言表现及其与脑电图特征的关系。
Epilepsy Behav. 2007 Mar;10(2):278-85. doi: 10.1016/j.yebeh.2006.12.003. Epub 2007 Jan 30.