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高龄是腹腔镜胆囊切除术的一个重要风险因素吗?

Is advanced age a significant risk factor for laparoscopic cholecystectomy?

作者信息

Yetim I, Dervisoglu A, Karaköse O, Buyukkaraba-Cak Y, Bek Y, Erzurumlu K

机构信息

Department of Surgery, Mustafa Kemal University Medical Faculty, Hatay, Turkey.

出版信息

Minerva Chir. 2010 Oct;65(5):507-13.

Abstract

AIM

have been a few reports about the outcome of laparoscopic cholecystectomy (LC) in the elderly patients. The aim of this study was to assess if morbidity and mortality may be increased in the geriatric patients because of high incidence of co-morbidity.

METHODS

From November 2000 to January 2009, 146 patients aged 60 years and older who underwent LC were reviewed. Patients were placed into two groups by ages: Group A (age = 60-74 years, N.=126), Group B (age ≥ 75, N.=20).

RESULTS

One hundred forty six patients underwent LC for benign gallbladder disease during this study period There was no difference in operative time, ASA, distribution of sex between the two groups. Most patients were treated with LC for symptomatic cholelithiasis (82.5%) in both groups. There were sixty eight cases (53.96%) in the Group A and 14 (70%) patients in the Group B had co-morbid diseases (P>0.005). Conversion rates and morbidity was not different significantly according to ages for either group (P>0.05). The rate of conversion to OC was 9.5% in the Group A and 5% in the Group B. Five complications were occurred in the four patients. There was only one bile duct injury in the Group A. Conversion rates and postoperative complications were not affected by gender and co-morbid diseases (P>0.05) in our study whereas acute cholecystitis were found as a risk factor for conversion to open surgery and complications according to the cases preoperatively diagnosis (P=0.001).

CONCLUSION

LC should be recommended with acceptable morbidity and mortality in the elderly. Morbidity and conversion to OC are not increased with advanced age even in the extremely elderly patients. Acute cholecystitis is correlated with a high risk factor for morbidity and conversion to OC.

摘要

目的

已有一些关于老年患者腹腔镜胆囊切除术(LC)结局的报道。本研究的目的是评估由于合并症发生率高,老年患者的发病率和死亡率是否可能增加。

方法

回顾2000年11月至2009年1月期间接受LC的146例60岁及以上患者。根据年龄将患者分为两组:A组(年龄=60 - 74岁,N = 126),B组(年龄≥75岁,N = 20)。

结果

在本研究期间,146例患者因良性胆囊疾病接受了LC。两组之间手术时间、美国麻醉医师协会(ASA)分级、性别分布无差异。两组中大多数患者因有症状的胆石症接受LC治疗(82.5%)。A组有68例(53.96%),B组有14例(70%)患者有合并症(P>0.005)。两组的中转率和发病率按年龄无显著差异(P>0.05)。A组中转开腹手术的发生率为9.5%,B组为5%。4例患者发生了5例并发症。A组仅发生1例胆管损伤。在我们的研究中,中转率和术后并发症不受性别和合并症影响(P>0.05),而根据术前诊断的病例,急性胆囊炎是中转开腹手术和并发症的危险因素(P = 0.001)。

结论

对于老年人,应推荐LC,其发病率和死亡率可接受。即使是极高龄患者,发病率和中转开腹手术率也不会因年龄增长而增加。急性胆囊炎与发病率和中转开腹手术的高风险因素相关。

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