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老年急性胆囊炎的腹腔镜胆囊切除术:100例患者的回顾性研究

Laparoscopic cholecystectomy for acute cholecystitis in the elderly: a retrospective study of 100 patients.

作者信息

Moyson J, Thill V, Simoens Ch, Smets D, Debergh N, Mendes da Costa P

机构信息

Department of Digestive, Laparoscopic and Thoracic Surgery C.H.U. Brugmann, U.L.B., Brussels, Belgium.

出版信息

Hepatogastroenterology. 2008 Nov-Dec;55(88):1975-80.

PMID:19260462
Abstract

BACKGROUND

The objective of this retrospective study is to evaluate the use oflaparoscopic cholecystectomy in the treatment of acute cholecystitis in elderly patients, and to identify risk factors for mortality.

METHODOLOGY

In this study we have included patients with acute cholecystitis aged 75 years and older. Patients were diagnosed after anatomical and pathological examination of an operative sample. We retrospectively examined 100 patients who underwent cholecystectomy between June 1991 and February 2007. Seventy-nine patients (79%) underwent laparoscopic cholecystectomy, 12 patients (12%) needed a conversion, and 15 patients (15%) were considered unfit to undergo a laparoscopic approach, due to their hemodynamic condition or for other reasons.

RESULTS

American Society of Anesthesiologists Scores (ASA), inflammatory syndrome, length of postoperative stay, number of days in the Intensive Care Unit, local complications, and mortality rate are all significantly higher in the 'laparotomy and conversion'. There was not a significant difference in age or general complications between groups. The mortality risk factors include a high level of CRP, biliary peritonitis, emergency, and the necessity of laparotomy.

CONCLUSION

Acute cholecystitis is a severe pathology in the elderly associated with a high rate of morbidity and mortality. Due to the mortality risk factors associated with acute cholecystitis, we recommend elective laparoscopic cholecystectomy for aged patients with symptomatic cholelithiasis, due to its low morbidity and mortality rates.

摘要

背景

本回顾性研究的目的是评估腹腔镜胆囊切除术在老年急性胆囊炎治疗中的应用,并确定死亡风险因素。

方法

本研究纳入了75岁及以上的急性胆囊炎患者。患者经手术标本的解剖和病理检查后确诊。我们回顾性研究了1991年6月至2007年2月间接受胆囊切除术的100例患者。79例(79%)患者接受了腹腔镜胆囊切除术,12例(12%)需要中转开腹,15例(15%)因血流动力学状况或其他原因被认为不适合行腹腔镜手术。

结果

“开腹及中转开腹”组的美国麻醉医师协会评分(ASA)、炎症综合征、术后住院时间、重症监护病房天数、局部并发症及死亡率均显著更高。两组间年龄或全身并发症无显著差异。死亡风险因素包括高CRP水平、胆汁性腹膜炎、急诊手术以及开腹手术的必要性。

结论

急性胆囊炎在老年人中是一种严重疾病,发病率和死亡率较高。鉴于与急性胆囊炎相关的死亡风险因素,我们建议对有症状胆石症的老年患者行择期腹腔镜胆囊切除术,因其发病率和死亡率较低。

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Hepatogastroenterology. 2008 Nov-Dec;55(88):1975-80.
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