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使用线束剂量分析工具(MDAT)来量化相邻切线和锁骨上放射野之间区域的剂量均匀性。

Use of a matchline dosimetry analysis tool (MDAT) to quantify dose homogeneity in the region between abutting tangential and supraclavicular radiation fields.

机构信息

Department of Imaging Physics, The University of Texas M. D. Anderson Cancer Center, Houston, TX, USA.

出版信息

J Appl Clin Med Phys. 2010 Jul 27;11(4):3294. doi: 10.1120/jacmp.v11i4.3294.

Abstract

In this work, we develop and test a matchline dosimetry analysis tool (MDAT) to examine the dose distribution within the abutment region of two or more adjoining radiotherapy fields that employ different blocking mechanisms and geometries in forming a match. This objective and quantitative tool uses calibrated radiographic film to measure the dose in the abutment region, and uses a frequency distribution of area versus dose (a dose-area histogram) to visualize the spatial dose distribution. We tested the MDAT's clinical applicability and parameters by evaluating the dose between adjacent photon fields incident on a flat phantom using field-matching techniques employing collimator-jaw and multileaf collimator (MLC) configurations. Additionally, we evaluated the dose in the abutment regions of four different clinical tangential-breast and supraclavicular matching techniques using various combinations of collimator and MLC matches. Using the MDAT tool, it was deter-mined that a 1 cm abutment region width (centered about the theoretical matchline between fields) is the most appropriate width to determine dose homogeneity in a field matching region. Using the MDAT, both subtle and large differences were seen between fields that used MLCs to form the match, compared to flat edge devices such as collimators and external cerrobend blocks. We conclude that the MDAT facilitates a more precise evaluation of the distribution of dose within the region of abutment of radiotherapy fields.

摘要

在这项工作中,我们开发并测试了一种匹配线剂量分析工具(MDAT),以检查使用不同阻挡机制和几何形状形成匹配的两个或更多相邻放射治疗场在毗邻区域内的剂量分布。这个客观和定量的工具使用校准的射线照相胶片来测量毗邻区域的剂量,并使用面积与剂量的频率分布(剂量-面积直方图)来可视化空间剂量分布。我们通过使用准直器-牙和多叶准直器(MLC)配置的场匹配技术评估平坦体模上相邻光子场之间的剂量,来测试 MDAT 的临床适用性和参数。此外,我们还使用各种准直器和 MLC 匹配组合,评估了四个不同临床切线乳房和锁骨上匹配技术的毗邻区域的剂量。使用 MDAT 工具,确定 1 厘米毗邻区域宽度(位于场之间的理论匹配线中心)是确定场匹配区域内剂量均匀性的最合适宽度。使用 MDAT,可以看到使用 MLC 形成匹配的场之间存在细微和明显的差异,而与准直器和外部 Cerrobend 块等平面边缘设备相比。我们得出结论,MDAT 有助于更精确地评估放射治疗场毗邻区域内的剂量分布。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4409/5720407/2ac55198b5d9/ACM2-11-206-g001.jpg

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