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用于实施调强放射治疗的动态模式下的多叶准直器系统的物理和剂量学方面。

Physical and dosimetric aspects of a multileaf collimation system used in the dynamic mode for implementing intensity modulated radiotherapy.

作者信息

LoSasso T, Chui C S, Ling C C

机构信息

Department of Medical Physics, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA.

出版信息

Med Phys. 1998 Oct;25(10):1919-27. doi: 10.1118/1.598381.

Abstract

The use of a multileaf collimator in the dynamic mode to perform intensity modulated radiotherapy became a reality at our institution in 1995. Unlike treatment with static fields using a multileaf collimator, there are significant dosimetric issues which must be assessed before dynamic therapy can be implemented. We have performed a series of calculations and measurements to quantify head scatter for small fields, collimator transmission, and the transmission through rounded leaf ends. If not accounted for, these factors affect the delivered dose to the prostate by 5%-20% for a typical plan. Data obtained with ion chambers and radiographic film are presented for both 6 and 15 MV x-ray beams. The impact on the delivered dose of the mechanical accuracy of the multileaf collimator, achieved during leaf position calibration and maintained during dose delivery, is also discussed.

摘要

1995年,在我们机构,使用多叶准直器在动态模式下进行调强放射治疗成为了现实。与使用多叶准直器的静态射野治疗不同,在实施动态治疗之前,必须评估一些重要的剂量学问题。我们进行了一系列计算和测量,以量化小射野的机头散射、准直器透射率以及通过圆形叶端的透射率。如果不考虑这些因素,对于一个典型的计划,这些因素会使前列腺的 delivered dose 受到5%-20%的影响。给出了使用电离室和放射胶片获得的6和15 MV X射线束的数据。还讨论了在叶片位置校准期间实现并在剂量输送期间保持的多叶准直器机械精度对 delivered dose 的影响。

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