Jahn K, Dichgans M
Neurologische Klinik und Poliklinik, Klinikum der Universität München.
Dtsch Med Wochenschr. 2010 Nov;135(47):2347-52. doi: 10.1055/s-0030-1267521. Epub 2010 Nov 16.
Cardial diseases are common causes of neurological emergencies. On the other hand, acute neurological disorders go along with systemic abnormalities, in particular they show cardial and pulmonary complications. This review is focused on the cardial consequences of cerebral lesions. Independent on the etiology of the brain disorder, the central activation of the adrenergic system plays a key role in the pathophysiology. The adrenergic stimulation modulates cardial function. ECG-changes, elevated cardial enzymes, arrhythmias, and sudden cardial death can be the consequences. In these cases, the adequate treatment of the neurological disorder is essential for the improvement of systemic symptoms. The cardial disorders (apical ballooning cardiomyopathy, neurogenic pulmonary edema) then have a favourable prognosis. For future studies on treatment of neurogenic-cardial disorders, the classification of the differently defined disorders based on their common pathophysiology will be essential.
心脏疾病是神经急症的常见病因。另一方面，急性神经障碍会伴有全身异常，尤其是会出现心脏和肺部并发症。本综述聚焦于脑损伤的心脏后果。无论脑部疾病的病因如何，肾上腺素能系统的中枢激活在病理生理学中都起着关键作用。肾上腺素能刺激会调节心脏功能。心电图改变、心肌酶升高、心律失常和心源性猝死都可能是其后果。在这些情况下，对神经障碍进行恰当治疗对于改善全身症状至关重要。心脏疾病（心尖球囊样心肌病、神经源性肺水肿）随后会有良好的预后。对于未来神经源性心脏疾病的治疗研究，基于其共同病理生理学对不同定义的疾病进行分类将至关重要。
