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双侧同期输尿管镜检查治疗输尿管结石:危险因素的批判性分析

Bilateral same-session ureteroscopy for treatment of ureteral calculi: critical analysis of risk factors.

作者信息

El-Hefnawy Ahmed S, El-Nahas Ahmed R, El-Tabey Nasr A, Shoma Ahmed M, El-Assmy Ahmed M, El-Kenawy Mahmoud R, El-Kappany Hamdy A, Eraky Ibrahim

机构信息

Urology and Nephrology Center, Mansoura University, Mansoura, Egypt.

出版信息

Scand J Urol Nephrol. 2011 Mar;45(2):97-101. doi: 10.3109/00365599.2010.530612. Epub 2010 Nov 17.

Abstract

OBJECTIVE

To determine factors affecting the success of bilateral same-session ureteroscopy (BSU) in the treatment of ureteral calculi.

MATERIAL AND METHODS

From January 2003 to December 2008, BSU was carried out in 89 patients (178 renal units). A successful outcome was considered when both ureters were free of stones without intraoperative complications. Stone-free rate was evaluated with a kidney-ureter-bladder plain X-ray or non-contrast computed tomography. Factors interfering with successful completion of BSU were tested using univariate (chi-squared test and t test) and multivariate (logistic regression) analyses. Data on unilateral ureteroscopy for the treatment of multiple ureteral calculi carried out in 105 patients during the same period were compared with BSU.

RESULTS

Intraoperative complications were recorded in 11 procedures (6.2%) in the form of ureteral perforation in three and mucosal injury in eight. After BSU, 153 renal units were stone free (86%) as 17 had residual fragments, stones migrated to the kidney in six and failure was encountered in two. A successful outcome was observed in 62 patients (70%). Stone impaction, stones located in the proximal ureter and stone surface area were the significant risk factors for unsuccessful BSU (relative risks 3.6, 3.3 and 1.47, respectively). Compared with unilateral ureteroscopy, no difference were found with regard to complication rate (6.7%, p = 0.5) or stone-free rate (80%, p = 0.2).

CONCLUSIONS

Bilateral same-session ureteroscopy is a safe and effective procedure in the management of bilateral ureteral stones. Proximal ureteral calculi, large and impacted stones carry the highest risk of unsuccessful results.

摘要

目的

确定影响双侧同期输尿管镜检查(BSU)治疗输尿管结石成功率的因素。

材料与方法

2003年1月至2008年12月,对89例患者(178个肾单位)实施了BSU。若双侧输尿管均无结石且无术中并发症,则认为治疗成功。通过肾脏-输尿管-膀胱平片或非增强计算机断层扫描评估结石清除率。使用单因素分析(卡方检验和t检验)和多因素分析(逻辑回归)来检测影响BSU成功完成的因素。将同期105例患者接受的单侧输尿管镜治疗多发性输尿管结石的数据与BSU进行比较。

结果

11例手术(6.2%)记录有术中并发症,其中3例为输尿管穿孔,8例为黏膜损伤。BSU术后,153个肾单位无结石(86%),17个有残留碎片,6个结石迁移至肾脏,2例治疗失败。62例患者(70%)治疗成功。结石嵌顿、位于输尿管上段的结石以及结石表面积是BSU失败的显著危险因素(相对风险分别为3.6、3.3和1.47)。与单侧输尿管镜检查相比,并发症发生率(6.7%,p = 0.5)或结石清除率(80%,p = 0.2)无差异。

结论

双侧同期输尿管镜检查是治疗双侧输尿管结石的一种安全有效的方法。输尿管上段结石、大的嵌顿性结石导致治疗失败的风险最高。

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