Department of Child and Adolescent Psychiatry, Division of Allergy and Chest Diseases, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.
Br J Dermatol. 2011 Jun;164(6):1342-7. doi: 10.1111/j.1365-2133.2010.10138.x. Epub 2011 May 13.
Several studies reported that adults with chronic idiopathic urticaria (CIU) frequently exhibit psychiatric comorbidity, most commonly depression and anxiety disorders. However the literature about children is limited.
To investigate the frequency of psychiatric disorders and to determine the levels of depression, anxiety and behavioural problems in a group of children with CIU.
The study included 27 children with CIU and 27 age- and sex-matched healthy subjects. Psychiatric assessment was done by using the Schedule for Affective Disorders and Schizophrenia for School Age Children-Present and Lifetime Version (K-SADS-PL). The State-Trait Anxiety Inventory for Children (STAI-C), Children's Depression Inventory (CDI) and Child Behavior Checklist (CBCL) were used to examine the levels of depression, anxiety and behavioural behaviours, respectively.
The study group had more frequent psychiatric diagnoses than the control group (70% vs. 30%) and the most common psychiatric disorders were social anxiety disorder, separation anxiety disorder and specific phobia. Depression, trait anxiety, internalizing problems, somatic complaints and anxiety/depressed scores were significantly higher in children with CIU. No correlation was found between the severity and duration of illness and psychological functioning.
This study showed that children with CIU had high psychiatric morbidity. The results suggest that the psychological status of children with CIU should be screened by clinicians and that an interdisciplinary approach combining dermatological and psychiatric evaluations is necessary for the management of CIU.
多项研究报告称,慢性特发性荨麻疹(CIU)成人常伴有精神共病,最常见的是抑郁和焦虑障碍。然而,关于儿童的文献有限。
调查一组 CIU 儿童的精神障碍频率,并确定其抑郁、焦虑和行为问题的水平。
本研究纳入了 27 名 CIU 患儿和 27 名年龄和性别匹配的健康对照者。采用儿童情感障碍和精神分裂症诊断定式检查(K-SADS-PL)进行精神病学评估。采用状态-特质焦虑量表儿童版(STAI-C)、儿童抑郁量表(CDI)和儿童行为检查表(CBCL)分别评估抑郁、焦虑和行为行为水平。
研究组的精神病诊断频率高于对照组(70% vs. 30%),最常见的精神障碍为社交焦虑障碍、分离焦虑障碍和特定恐惧症。CIU 患儿的抑郁、特质焦虑、内化问题、躯体抱怨和焦虑/抑郁评分显著更高。疾病严重程度和持续时间与心理功能之间无相关性。
本研究表明,CIU 患儿存在较高的精神发病。结果提示,临床医生应筛查 CIU 患儿的心理状态,并且需要结合皮肤科和精神科评估的多学科方法来管理 CIU。