Liakopoulou M, Alifieraki T, Katideniou A, Kakourou T, Tselalidou E, Tsiantis J, Stratigos J
Athens University Medical School, Greece.
J Am Acad Child Adolesc Psychiatry. 1997 May;36(5):678-84. doi: 10.1097/00004583-199705000-00019.
To examine the nature of psychopathology of children with alopecia areata (AA) and to investigate the frequency and quality of life events in the year before AA developed in comparison with a control group.
Thirty-three subjects with AA, mean age 10.5 +/- 0.3 years, were compared with 30 controls who visited a pediatrician for a mild condition. In addition, 16 preschool children with AA were compared with 17 preschool children who visited the pediatrician for a mild condition. The following measures were used: Child Psychiatric Interview, Children's Depression Inventory (CDI), Children's Manifest Anxiety Scale (CMAS), Life Events Scale for Children, and Child Behavior Checklist (CBCL).
On the CBCL, children with AA had more psychological problems, in total, than controls, and in particular, they were more anxious or depressed, withdrawn, aggressive, and delinquent. They also had more somatic problems as well as problems in social relations and in attention. Girls with AA seem to have been affected more in dimensions of total problems, anxiety/depression, and internalizing/externalizing syndromes. In terms of anxiety (CMAS), more children with AA than controls seemed to worry and to have difficulties in concentration and physiological symptoms of anxiety. In the Child Psychiatric Interview, all children with AA exhibited symptomatology of anxiety or depression or both, usually of mild or moderate nature. Major depression was not detected through the CDI. Fewer children with AA had positive life events the year before AA than controls in a similar time period.
Compared with controls, children with AA had more psychiatric symptoms in general and symptoms of anxiety or depression, or both, in particular. There is also evidence that lack of positive life events in the prealopecia period played a role in their lives. Psychiatric assessment, and if necessary treatment, is warranted for all children with this condition.
研究斑秃（AA）患儿的精神病理学本质，并调查与对照组相比，AA发病前一年生活事件的频率和生活质量。
将33名平均年龄为10.5±0.3岁的AA患儿与30名因轻症就诊于儿科医生的对照组儿童进行比较。此外，将16名学龄前AA患儿与17名因轻症就诊于儿科医生的学龄前儿童进行比较。采用以下测量方法：儿童精神病访谈、儿童抑郁量表（CDI）、儿童显性焦虑量表（CMAS）、儿童生活事件量表和儿童行为清单（CBCL）。
在CBCL上，AA患儿总体上比对照组有更多心理问题，尤其是他们更焦虑或抑郁、孤僻、攻击性强和有违纪行为。他们在躯体问题、社会关系和注意力方面也有更多问题。AA女童在总问题、焦虑/抑郁以及内化/外化综合征维度上似乎受影响更大。在焦虑方面（CMAS），AA患儿中比对照组更多的儿童似乎会担心，并且在注意力集中和焦虑的生理症状方面有困难。在儿童精神病访谈中，所有AA患儿均表现出焦虑或抑郁症状，或两者皆有，通常为轻度或中度。通过CDI未检测到重度抑郁。与对照组在相似时间段内相比，AA患儿在AA发病前一年有积极生活事件的人数更少。
与对照组相比，AA患儿总体上有更多精神症状，尤其是焦虑或抑郁症状，或两者皆有。也有证据表明，脱发前期缺乏积极生活事件对他们的生活产生了影响。所有患此病的儿童都需要进行精神评估，必要时进行治疗。
