Santos M T B R, Ferreira M C D, Leite M F, Guaré R O
Discipline of Dentistry, Persons with Disabilities Division, Universidade Cruzeiro do Sul, São Paulo, Brazil.
Child Care Health Dev. 2011 May;37(3):404-9. doi: 10.1111/j.1365-2214.2010.01176.x. Epub 2010 Nov 18.
Although drooling of saliva is considered abnormal in a child over 4 years of age, it has been estimated to occur in approximately in 10-37% of children with cerebral palsy.
The aim of this study was to evaluate the flow rate, pH and buffering capacity in saliva of Brazilian individuals with cerebral palsy who drool.
Cross-sectional assessment of saliva from 139 individuals with cerebral palsy (3-16 years old) enrolled in a specialized rehabilitation centre in Sao Paulo, Brazil, divided into two groups, according to the presence (G1) or absence (G2) of drooling and controls (G3): G1 consisted of 63 individuals who drool; G2 consisted of 76 who do not drool; and G3 consisted of 47 individuals with no neurological damage of similar age and sex. Unstimulated whole saliva was collected and salivary flow rate (mL/min), initial pH and buffering capacity, by titration of saliva with a constant amount of 0.01 N HCl, were evaluated. The results from G1, G2 and G3 were compared by one-way anova and the χ(2) -test.
A higher percentage of severe drooling (60.3%) was observed compared with moderate (27.0%) and mild (12.7%) in the cerebral palsy individuals who drool and the prevalence of drooling was highest among children and adolescents with spastic quadriplegia. Significant reductions in salivary flow rate, initial pH, buffering capacity of whole saliva in pH range 6.0-6.9 and total buffering capacity occurred in G1 and G2 compared with G3.
All individuals with cerebral palsy present lower flow rate, pH and buffering capacity of saliva, which increases the risk of oral diseases.
尽管4岁以上儿童流口水被视为异常，但据估计，约10%-37%的脑瘫患儿会出现流口水现象。
本研究旨在评估巴西流口水的脑瘫患者唾液的流速、pH值和缓冲能力。
对巴西圣保罗一家专业康复中心收治的139例脑瘫患者（3-16岁）的唾液进行横断面评估，根据是否流口水分为两组，即流口水组（G1）、不流口水组（G2）和对照组（G3）：G1组由63例流口水患者组成；G2组由76例不流口水患者组成；G3组由47例年龄和性别相仿且无神经损伤的个体组成。收集非刺激性全唾液，评估唾液流速（mL/分钟）、初始pH值和缓冲能力（通过用恒量0.01N HCl滴定唾液来评估）。通过单因素方差分析和χ²检验比较G1、G2和G3组的结果。
在流口水的脑瘫患者中，重度流口水的比例（60.3%）高于中度（27.0%）和轻度（12.7%），且流口水在痉挛性四肢瘫的儿童和青少年中最为常见。与G3组相比，G1组和G2组的唾液流速、初始pH值、pH值在6.0-6.9范围内的全唾液缓冲能力和总缓冲能力均显著降低。
所有脑瘫患者的唾液流速、pH值和缓冲能力均较低，这增加了患口腔疾病的风险。
