Toll样受体4基因多态性对幽门螺杆菌循环抗体水平的影响。 - Suppr

Impact of TLR-4 polymorphisms on circulating levels of antibodies against Helicobacter pylori.

作者信息

Manolakis Anastassios C, Kapsoritakis Andreas N, Tiaka Elisavet K, Satra Maria, Gerovassili Aggeliki, Tsiompanidis Ilias, Vamvakopoulos Nikolaos, Potamianos Spyros P

出版信息

Helicobacter. 2010 Oct;15(5):481-2. doi: 10.1111/j.1523-5378.2010.00785.x.

DOI:10.1111/j.1523-5378.2010.00785.x

PMID:21083756

Abstract

摘要

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Impact of TLR-4 polymorphisms on circulating levels of antibodies against Helicobacter pylori.Toll样受体4基因多态性对幽门螺杆菌循环抗体水平的影响。

Helicobacter. 2010 Oct;15(5):481-2. doi: 10.1111/j.1523-5378.2010.00785.x.

Association of Toll-like receptor-4 (Asp299Gly and Thr399Ileu) gene polymorphisms with gastritis and precancerous lesions.Toll样受体4（Asp299Gly和Thr399Ileu）基因多态性与胃炎及癌前病变的关联

Hum Immunol. 2007 Nov;68(11):901-7. doi: 10.1016/j.humimm.2007.10.006. Epub 2007 Nov 5.

Interaction between CD14-159C>T polymorphism and Helicobacter pylori is associated with serum total immunoglobulin E.CD14基因159C>T多态性与幽门螺杆菌之间的相互作用与血清总免疫球蛋白E相关。

Clin Exp Allergy. 2008 Dec;38(12):1929-34. doi: 10.1111/j.1365-2222.2008.03103.x.

Genetic polymorphisms of NOD1 and IL-8, but not polymorphisms of TLR4 genes, are associated with Helicobacter pylori-induced duodenal ulcer and gastritis.NOD1和IL-8的基因多态性与幽门螺杆菌诱导的十二指肠溃疡和胃炎相关，而TLR4基因的多态性则与之无关。

Helicobacter. 2007 Apr;12(2):124-31. doi: 10.1111/j.1523-5378.2007.00481.x.

Polymorphism of the Helicobacter pylori feoB gene in Korea: a possible relation with iron-deficiency anemia?韩国幽门螺杆菌feoB基因的多态性：与缺铁性贫血是否存在潜在关联？

Helicobacter. 2004 Aug;9(4):330-4. doi: 10.1111/j.1083-4389.2004.00239.x.

Toll-like receptor (TLR) 2 induced through TLR4 signaling initiated by Helicobacter pylori cooperatively amplifies iNOS induction in gastric epithelial cells.由幽门螺杆菌引发的Toll样受体4（TLR4）信号传导所诱导的Toll样受体2（TLR2），协同增强胃上皮细胞中诱导型一氧化氮合酶（iNOS）的诱导作用。

Am J Physiol Gastrointest Liver Physiol. 2007 Nov;293(5):G1004-12. doi: 10.1152/ajpgi.00096.2007. Epub 2007 Sep 13.

Genetic polymorphisms of the cancer related gene and Helicobacter pylori infection in Japanese gastric cancer patients. An age and gender matched case-control study.日本胃癌患者中癌症相关基因的遗传多态性与幽门螺杆菌感染。一项年龄和性别匹配的病例对照研究。

Cancer. 1996 Apr 15;77(8 Suppl):1654-61. doi: 10.1002/(SICI)1097-0142(19960415)77:8<1654::AID-CNCR35>3.0.CO;2-X.

Evolution of bacterial genes: evidences of positive Darwinian selection and fixation of base substitutions in virulence genes of Helicobacter pylori.细菌基因的进化：幽门螺杆菌毒力基因中正向达尔文选择和碱基替换固定的证据。

Infect Genet Evol. 2010 Aug;10(6):764-76. doi: 10.1016/j.meegid.2010.04.005. Epub 2010 Apr 29.

Effects of toll-like receptor-4 gene polymorphisms on soluble P-selectin and von Willebrand factor levels in hypercholesterolemic patients.Toll样受体4基因多态性对高胆固醇血症患者可溶性P-选择素和血管性血友病因子水平的影响。

Thromb Haemost. 2007 Sep;98(3):642-6.

Toll-like receptor 4 (TLR4) gene polymorphisms in celiac disease.乳糜泻中Toll样受体4（TLR4）基因多态性

Tissue Antigens. 2007 Dec;70(6):495-8. doi: 10.1111/j.1399-0039.2007.00945.x. Epub 2007 Oct 8.

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Genetic Variability as a Regulator of TLR4 and NOD Signaling in Response to Bacterial Driven DNA Damage Response (DDR) and Inflammation: Focus on the Gastrointestinal (GI) Tract.遗传变异性作为Toll样受体4（TLR4）和核苷酸结合寡聚化结构域（NOD）信号传导的调节因子，在应对细菌驱动的DNA损伤反应（DDR）和炎症中的作用：聚焦于胃肠道（GI）。

Front Genet. 2017 May 29;8:65. doi: 10.3389/fgene.2017.00065. eCollection 2017.

Readressing the role of Toll-like receptor-4 alleles in inflammatory bowel disease: colitis, smoking, and seroreactivity.纠正 Toll 样受体 4 等位基因在炎症性肠病中的作用：结肠炎、吸烟和血清反应性。

Dig Dis Sci. 2013 Feb;58(2):371-80. doi: 10.1007/s10620-012-2348-4. Epub 2012 Aug 24.

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Impact of TLR-4 polymorphisms on circulating levels of antibodies against Helicobacter pylori.

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