Department of Cardiology, West German Heart Center, University Clinic Duisburg-Essen, Hufelandstrasse 55, 45122 Essen, Germany.
Radiology. 2010 Dec;257(3):614-23. doi: 10.1148/radiol.10100140.
For selected indications, coronary computed tomographic (CT) angiography is an established clinical technology for evaluation in patients suspected of having or known to have coronary artery disease. In coronary CT angiography, image quality is highly dependent on heart rate, with heart rate reduction to less than 60 beats per minute being important for both image quality and radiation dose reduction, especially when single-source CT scanners are used. β-Blockers are the first-line option for short-term reduction of heart rate prior to coronary CT angiography. In recent years, multiple β-blocker administration protocols with oral and/or intravenous application have been proposed. This review article provides an overview of the indications, efficacy, and safety of β-blockade protocols prior to coronary CT angiography with respect to different scanner techniques. Moreover, implications for radiation exposure and left ventricular function analysis are discussed.
对于特定的适应证，冠状动脉 CT 血管造影（CTA）是一种成熟的临床技术，用于评估疑似或已知患有冠状动脉疾病的患者。在冠状动脉 CTA 中，图像质量高度依赖于心率，将心率降低至每分钟 60 次以下对于提高图像质量和减少辐射剂量都很重要，特别是在使用单源 CT 扫描仪时。β受体阻滞剂是在进行冠状动脉 CTA 前短期降低心率的首选药物。近年来，提出了多种口服和/或静脉应用的β受体阻滞剂给药方案。本文综述了不同 CT 扫描技术在冠状动脉 CTA 前应用β受体阻滞剂的适应证、疗效和安全性，并讨论了对辐射暴露和左心室功能分析的影响。
