Bornemann M
Department of Medicine, Tripler Army Medical Center, Honolulu, Hawaii 96859-5000.
South Med J. 1990 Apr;83(4):461-2. doi: 10.1097/00007611-199004000-00025.
This case of Conn's syndrome demonstrates long-term (seven years) efficacy of triamterene-thiazide therapy in controlling both hypertension and hypokalemia. Studies done before the adrenal tumor was removed surgically showed that the tumor had increased in size and function since the first studies were done before triamterene-thiazide therapy. The resolution of hypertension after nine years of hyperaldosteronism suggests that surgery is effective even after chronic hyperaldosteronism has been present for some time.
该例原发性醛固酮增多症(Conn综合征)病例表明,氨苯蝶啶 - 噻嗪类疗法在控制高血压和低钾血症方面具有长期(七年)疗效。在肾上腺肿瘤手术切除前进行的研究显示,自首次在氨苯蝶啶 - 噻嗪类疗法之前进行研究以来,肿瘤的大小和功能均有所增加。醛固酮增多症九年后高血压得到缓解,这表明即使在慢性醛固酮增多症已经存在一段时间后,手术仍然有效。