Singh Dilip, Sinha Manish, Kumar Rajesh, Shukla Rakesh, Ahuja R C
Department of Neurology, Chhatrapati Shahuji Maharaj Medical University, Lucknow, U.P., India.
Ann Indian Acad Neurol. 2010 Jul;13(3):211-2. doi: 10.4103/0972-2327.70876.
Opsoclonus-myoclonus syndrome (OMS) is a rare condition that has been reported from all parts of the world. It is well recognized as a paraneoplastic syndrome in children with neuroblastoma and in adults with small-cell carcinoma of lung and some other cancers. It may also occur in association with various central nervous system infections. We report a case of OMS in a patient with varicella zoster virus infection. IgM antibody for varicella-zoster virus was detected in the serum and the cerebrospinal fluid. The patient improved after treatment with clonazepam and was asymptomatic at 1-month follow-up.
眼阵挛-肌阵挛综合征(OMS)是一种已在世界各地均有报道的罕见病症。它在患有神经母细胞瘤的儿童以及患有肺小细胞癌和其他一些癌症的成人中被公认为一种副肿瘤综合征。它也可能与各种中枢神经系统感染有关。我们报告了一例患有水痘带状疱疹病毒感染的OMS患者。在血清和脑脊液中检测到了水痘带状疱疹病毒的IgM抗体。患者在使用氯硝西泮治疗后病情好转,在1个月的随访中无症状。