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水痘带状疱疹病毒引起的眼阵挛-肌阵挛综合征。

Opsoclonus-myoclonus syndrome caused by varicella-zoster virus.

作者信息

Singh Dilip, Sinha Manish, Kumar Rajesh, Shukla Rakesh, Ahuja R C

机构信息

Department of Neurology, Chhatrapati Shahuji Maharaj Medical University, Lucknow, U.P., India.

出版信息

Ann Indian Acad Neurol. 2010 Jul;13(3):211-2. doi: 10.4103/0972-2327.70876.

Abstract

Opsoclonus-myoclonus syndrome (OMS) is a rare condition that has been reported from all parts of the world. It is well recognized as a paraneoplastic syndrome in children with neuroblastoma and in adults with small-cell carcinoma of lung and some other cancers. It may also occur in association with various central nervous system infections. We report a case of OMS in a patient with varicella zoster virus infection. IgM antibody for varicella-zoster virus was detected in the serum and the cerebrospinal fluid. The patient improved after treatment with clonazepam and was asymptomatic at 1-month follow-up.

摘要

眼阵挛-肌阵挛综合征(OMS)是一种已在世界各地均有报道的罕见病症。它在患有神经母细胞瘤的儿童以及患有肺小细胞癌和其他一些癌症的成人中被公认为一种副肿瘤综合征。它也可能与各种中枢神经系统感染有关。我们报告了一例患有水痘带状疱疹病毒感染的OMS患者。在血清和脑脊液中检测到了水痘带状疱疹病毒的IgM抗体。患者在使用氯硝西泮治疗后病情好转,在1个月的随访中无症状。

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本文引用的文献

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Myoclonic encephalopathy of infants.婴儿肌阵挛性脑病
J Neurol Neurosurg Psychiatry. 1962 Aug;25(3):271-6. doi: 10.1136/jnnp.25.3.271.
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Paraneoplastic syndromes of the CNS.中枢神经系统副肿瘤综合征
Lancet Neurol. 2008 Apr;7(4):327-40. doi: 10.1016/S1474-4422(08)70060-7.
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Syndrome of opsoclonus-myoclonus caused by Coxsackie B3 infection.
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