心房颤动患者的卒中预防治疗：新旧方法。

Stroke prevention treatment of patients with atrial fibrillation: old and new.

机构信息

Departments of Clinical Neurosciences, Calgary Stroke Program, Faculty of Medicine, University of Calgary, Calgary, AB, Canada.

出版信息

Curr Neurol Neurosci Rep. 2011 Feb;11(1):15-27. doi: 10.1007/s11910-010-0161-z.

DOI:10.1007/s11910-010-0161-z

PMID:21086074

Abstract

Atrial fibrillation is the most common cause of cardioembolic ischemic stroke and has a rising prevalence worldwide. Stroke prevention in this condition is poised to take a substantial leap forward with the evolution of new anticoagulant medications, with superior properties compared to vitamin K antagonists. New, safer and more effective chronic therapy is on the horizon. However, many issues surrounding the management of stroke prevention after an acute stroke and during the course of chronic anticoagulant therapy remain to be resolved.

摘要

心房颤动是心源性栓塞性缺血性卒中的最常见病因，在全球的患病率呈上升趋势。随着新型抗凝药物的出现，其性能优于维生素 K 拮抗剂，这种情况下的卒中预防有望取得重大进展。新的、更安全和更有效的慢性治疗方法即将出现。然而，急性卒中后和慢性抗凝治疗过程中卒中预防管理仍存在许多问题有待解决。