Crochet D, Leurent B, Grossetete R
Centre hémodynamique-radiologie thoracique, CHR de Nantes.
Arch Mal Coeur Vaiss. 1990 Mar;83(3):315-20.
Between January 1986 and December 1988, 558 patients underwent percutaneous transluminal coronary angioplasty (PTCA) of whom 40 per cent were dilated at the time of diagnostic coronary arteriography. In order to assess the value of this therapeutic strategy we compared the results of 221 patients dilated at the time of diagnostic coronary arteriography (Group 1) with those of 337 patients who underwent deferred PTCA. In Group 1, the incidence of stable angina was lower (26.7% vs 46.3%, p less than 10-5), that of thrombolysed myocardial infarction was higher (24% vs 2.7%, p less than 10-9) and a higher proportion of patients had previously undergone PTCA (29.4% vs 3.2%, p less than 10-9). The proportion of patients with single vessel disease was higher in Group 1 (84.6% vs 74.7%, p less than 0.01) as was that of angioplasty of a single lesion (97.7% vs 88.1%, p less than 10-4). There were fewer dilations of the left circumflex artery in Group 1 (17.2% vs 27.3%, p less than 0.05) which was compensated by a higher number involving the right coronary artery (26.1% vs 15.5%, p less than 0.01). The immediate results were comparable in the two groups with 87.8 per cent primary successes, 3.6 per cent of myocardial infarcts and 1.3 per cent of coronary bypass operations with no fatalities in Group 1. These favorable results encourage the development of PTCA at the time of diagnostic coronary arteriography in the following indications: unstable angina, thrombolysed myocardial infarction and restenosis irrespective of the patient's symptomatology.(ABSTRACT TRUNCATED AT 250 WORDS)
1986年1月至1988年12月期间,558例患者接受了经皮腔内冠状动脉成形术(PTCA),其中40%在诊断性冠状动脉造影时进行了扩张。为了评估这一治疗策略的价值,我们将221例在诊断性冠状动脉造影时进行扩张的患者(第1组)的结果与337例接受延迟PTCA的患者的结果进行了比较。在第1组中,稳定型心绞痛的发生率较低(26.7%对46.3%,p<10⁻⁵),溶栓后心肌梗死的发生率较高(24%对2.7%,p<10⁻⁹),且先前接受过PTCA的患者比例更高(29.4%对3.2%,p<10⁻⁹)。第1组中单支血管病变患者的比例更高(84.6%对74.7%,p<0.01),单处病变血管成形术的比例也是如此(97.7%对88.1%,p<10⁻⁴)。第1组中左旋支动脉的扩张较少(17.2%对27.3%,p<0.05),这由右冠状动脉扩张数量的增加得到补偿(26.1%对15.5%,p<0.01)。两组的即刻结果具有可比性,第1组的主要成功率为87.8%,心肌梗死发生率为3.6%,冠状动脉搭桥手术发生率为1.3%,无死亡病例。这些良好结果鼓励在诊断性冠状动脉造影时针对以下指征开展PTCA:不稳定型心绞痛、溶栓后心肌梗死和再狭窄,无论患者症状如何。(摘要截选至250词)