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[活体供肾切除术:开放手术与腹腔镜技术]

[Living donor nephrectomy: open versus laparoscopic technique].

作者信息

Franceschin M, Capocasale E, Dalla Valle R, Mazzoni M P, Busi N, Sianesi M

出版信息

Urologia. 2009 Jan-Mar;76(1):36-40.

Abstract

The living donor nephrectomy has to be safe and effective, allowing a good graft function in the recipient. In the past, donor nephrectomy was performed only by open technique; more recently this nephrectomy has also been performed by laparoscopic technique. The best technique has not been established in literature. The purpose of this study is to report the results of open and laparoscopic nephrectomy in living donors. MATERIALS AND METHODS. From January 1992 to August 2008, 37 living donor nephrectomies were performed. 23 nephrectomies were achieved by laparoscopic procedure (LDN) and 14 by open technique (ODN). The 2 groups were comparable regarding both donor and recipient characteristics. RESULTS. All laparoscopic nephrectomies were successfully performed without conversion to open procedure. No donor deaths were reported in either groups. 3 complications (13%) in the LDN group and 1 (7.1%) in the ODN group (p=0.6) were observed. Mean operative time was higher in the LDN group (p<0.036). Mean warm and cold ischemia time, resumption of oral intake and hospital stay were shorter in the LDN group (p<0.04)( p<0.03) (p<0.0001), whereas the return to normal occupational life was similar (p<0.52). We had no significant differences in the surgical complication rates, graft and patient survival. CONCLUSIONS. Our experience suggests that both procedures can be used safely and efficiently, and assure a good renal function in the recipient. Laparoscopic nephrectomy, although more difficult, provides post-operative advantages. However, laparoscopic procedure must be performed by experienced centres only to prevent serious complications in the donor.

摘要

活体供肾肾切除术必须安全有效,以使受者获得良好的移植肾功能。过去,供肾肾切除术仅通过开放手术进行;最近,这种肾切除术也可通过腹腔镜技术完成。文献中尚未确立最佳技术。本研究的目的是报告活体供者开放和腹腔镜肾切除术的结果。材料与方法。1992年1月至2008年8月,共进行了37例活体供肾肾切除术。23例肾切除术通过腹腔镜手术(LDN)完成,14例通过开放手术(ODN)完成。两组在供者和受者特征方面具有可比性。结果。所有腹腔镜肾切除术均成功完成,未转为开放手术。两组均未报告供者死亡。LDN组观察到3例并发症(13%),ODN组观察到1例(7.1%)(p = 0.6)。LDN组平均手术时间更长(p < 0.036)。LDN组平均热缺血和冷缺血时间、恢复经口进食时间和住院时间更短(p < 0.04)(p < 0.03)(p < 0.0001),而恢复正常职业生活的情况相似(p < 0.52)。我们在手术并发症发生率、移植肾和患者生存率方面没有显著差异。结论。我们的经验表明,两种手术方法均可安全有效地使用,并确保受者获得良好的肾功能。腹腔镜肾切除术虽然更具难度,但具有术后优势。然而,腹腔镜手术必须仅由经验丰富的中心进行,以防止供者出现严重并发症。

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