Gorbacheva Iu V, Baranova O V, Shishkina L V, Pal'tseva E M, Egorov O E, Evzikova G Iu, Timoshenkov A V
Arkh Patol. 2010 Jul-Aug;72(4):52-5.
The authors report a rare a case of gliosarcoma metastases in a 28-year-old male patient. The cauda equina roots were involved after brain tumor 16 months ago, which, on microscopic study, had a biphasic pattern and heterogeneous staining in the reaction with antibody to GFAP and vimentin; the tumor cells did not express EMA, EA, and desmin. Gliosarcoma was diagnosed, by taking into account morphological and immunohistochemical data. Tumor tissue of the cauda equine roots had the same immunophenotype as the brain tumor with a predominance of glial component, which permitted the source of metastases to be ascertained.
