Colacurci N, De Franciscis P
Dipartimento di Scienze Ginecologiche, Ostetriche e della Riproduzione-Seconda Università di Napoli.
G Ital Med Lav Ergon. 2010 Oct-Dec;32(4):461-3.
Endocrine disruptors (EDs) are dangerous chemicals widely used daily and spread in the environment and able to impair male and female fertility by interfering with the endocrine regulation of reproductive system. Many epidemiological studies showed the role of the EDs in the pathogenesis of reproductive pathologies such as infertility, recurrent abortions, malformations and endometriosis. Personal data show a significant correlation between phthalates and bisphenols and endometriosis. Further studies are needed to assess a clear relationship between environmental exposure to ED and reproductive pathologies and to find exposure's markers for environmental pollutants in biological fluids with the aim to have useful instruments for monitoring and preserving the reproductive health of women at risk of occupational/environmental exposure to ED.
内分泌干扰物（EDs）是一类危险化学品，在日常生活中广泛使用，散布于环境中，能够通过干扰生殖系统的内分泌调节来损害男性和女性的生育能力。许多流行病学研究表明，内分泌干扰物在诸如不孕、反复流产、畸形和子宫内膜异位等生殖系统疾病的发病机制中发挥作用。个人数据显示，邻苯二甲酸盐和双酚与子宫内膜异位之间存在显著相关性。需要进一步开展研究，以评估环境暴露于内分泌干扰物与生殖系统疾病之间的明确关系，并寻找生物体液中环境污染物的暴露标志物，目的是获得有用的工具，用于监测和保护有职业性/环境性暴露于内分泌干扰物风险的女性的生殖健康。
