Kasum Miro
Human Reproduction Unit, University Department of Obstetrics and Gynecology, Zagreb University Hospital Center, Zagreb, Croatia.
Acta Clin Croat. 2010 Jun;49(2):197-200.
The prevalence of uterine myomas during pregnancy is estimated to range from 0.3% to 2.6%. Although leiomyomas usually remain asymptomatic, in one often cases they may be complicated. The management of uterine fibroids during pregnancy is largely conservative and surgical removal is generally delayed until post partum. A 37-year-old pregnant woman (15 weeks) with a history of gynecologic examination several hours before presented with lower abdominal pain and signs of acute abdomen. She was para-2, as she had delivered a healthy child 12 years before, and current pregnancy was uncomplicated until presentation. Intra-abdominal hemorrhage was suspected and she underwent immediate exploratory laparotomy, which revealed massive hemoperitoneum. A subserous uterine leiomyoma of 8.5x6.5 cm was found in the fundus area, with an actively bleeding ruptured vessel on its dome. Myomectomy was successfully performed and 1.5 liter of blood and blood clots were evacuated from the peritoneal cavity. The histology report showed sections of interlacing bundles of smooth muscles with areas of bleeding and necrotic degeneration. The postoperative course and subsequent antenatal period were uneventful. The woman went into spontaneous labor at 38 weeks and delivered vaginally a healthy male baby. This rare case ofintra-abdominal hemorrhage due to bleeding myoma supports other recent studies, which have demonstrated that myomectomy may be successfully performed during pregnancy in selected circumstances.
孕期子宫肌瘤的患病率估计在0.3%至2.6%之间。虽然平滑肌瘤通常无症状,但在许多情况下可能会出现并发症。孕期子宫肌瘤的处理大多采取保守治疗,手术切除一般推迟到产后。一名37岁孕妇(孕15周),数小时前有妇科检查史,现出现下腹痛及急腹症体征。她既往有2次分娩史,12年前曾分娩一健康婴儿,此次妊娠直至出现症状前均无并发症。怀疑有腹腔内出血,遂立即行剖腹探查术,术中发现大量腹腔积血。在子宫底部发现一个8.5×6.5厘米的浆膜下子宫肌瘤,肌瘤顶部有一活动性出血的破裂血管。成功实施了肌瘤切除术,从腹腔内清除了1.5升血液和血凝块。组织学报告显示为交错排列的平滑肌束切片,伴有出血和坏死性退变区域。术后过程及随后的孕期均顺利。该妇女在38周时自然临产,经阴道分娩一健康男婴。这例因肌瘤出血导致腹腔内出血的罕见病例支持了其他近期研究,这些研究表明在某些特定情况下,孕期可行肌瘤切除术。