Ireland J, Wilsher M
Green Lane Respiratory Services, Auckland District Health Board, Auckland, New Zealand.
Sarcoidosis Vasc Diffuse Lung Dis. 2010 Jul;27(1):36-42.
Sarcoidosis is a chronic multisystem disease with a high prevalence of depression although this is often not recognised. It is not known how patients perceive their disease or the medications required for treatment. We hypothesised that perceptions of illness and beliefs about medications may relate to psychological distress in this condition.
81(42 female) patients with sarcoidosis completed the following: Hospital Anxiety and Depression Scale, Illness Perception Questionnaire, Beliefs about Medications Questionnaire. Demographic and clinical data were collected and the physician's perception of symptom severity and relationship to sarcoidosis recorded.
The prevalence of depression (23%) and anxiety (33%) was high and related to self reported symptoms of sarcoidosis. Those on current treatment reported different illness perceptions than those not, and illness perceptions related to anxiety and depression scores. The majority of the sample felt that sarcoid medications were unnecessary but few patients reported concerns about potential adverse consequences of taking them. Beliefs about medications were related to illness perceptions but not associated with anxiety or depression scores or with clinical perception of disease state. There were significant gender differences in perceptions of illness and beliefs about medications.
These data confirm earlier reports that anxiety and depression are common in patients with sarcoidosis and in turn perceptions of illness impact on emotional wellness in this disorder. Use of the Illness Perceptions Questionnaire in clinical practice may help to identify those patients who would benefit from interventions to change their perceptions of illness.
结节病是一种慢性多系统疾病，抑郁症患病率较高，尽管这一点常常未被认识到。目前尚不清楚患者如何看待自己的疾病以及治疗所需的药物。我们推测，在这种情况下，对疾病的认知和对药物的看法可能与心理困扰有关。
81名（42名女性）结节病患者完成了以下问卷：医院焦虑抑郁量表、疾病认知问卷、药物看法问卷。收集了人口统计学和临床数据，并记录了医生对症状严重程度以及与结节病关系的认知。
抑郁症患病率（23%）和焦虑症患病率（33%）较高，且与结节病的自我报告症状相关。正在接受治疗的患者与未接受治疗的患者对疾病的认知不同，疾病认知与焦虑和抑郁评分相关。大多数样本认为结节病药物不必要，但很少有患者报告担心服用这些药物的潜在不良后果。对药物的看法与疾病认知相关，但与焦虑或抑郁评分以及疾病状态的临床认知无关。在疾病认知和对药物的看法方面存在显著的性别差异。
这些数据证实了早期报告，即焦虑和抑郁在结节病患者中很常见，反过来，疾病认知会影响这种疾病中的情绪健康。在临床实践中使用疾病认知问卷可能有助于识别那些将从改变疾病认知的干预措施中受益的患者。
