Key Laboratory of Colloid and Interface Chemistry, Shandong University, Ministry of Education, Jinan 250100, China.
Langmuir. 2010 Dec 21;26(24):18652-8. doi: 10.1021/la102847f. Epub 2010 Nov 18.
The effects of hydrophilic headgroups of Ca surfactants, calcium dodecylsulfate (Ca(DS)(2)), calcium dodecylsulfonate (Ca(DSA)(2)), and calcium laurate (CaL(2)) and hydrophobic chains of alkyldimethylamine oxide (C(n)DMAO, n = 12, 14, 16) on the formation of Ca(2+)-ligand coordinated vesicles was investigated in detail. On the basis of phase behavior studies, rheological properties and freeze-fracture transmission electron microscope (FF-TEM) images were measured. Quite different phase behaviors were observed in different surfactant systems. For a Ca surfactant with a highly polar group, Ca(DS)(2), vesicles were observed in all Ca(DS)(2)/C(n)DMAO (n = 12, 14, and 16) systems, whereas for Ca surfactant with lower polar group, Ca(DSA)(2), vesicles can form in Ca(DSA)(2)/C(n)DMAO systems of n = 14 and 16 but not for n = 12. For CaL(2), the surfactant with the least polar group, vesicles form only in the CaL(2)/C(16)DMAO system. The results demonstrate that in the systems formed by Ca surfactants and C(n)DMAO, the formation of vesicles is driven not only by interaction between Ca(2+) and the N → O groups of C(n)DMAO but also by electrostatic and hydrophobic interactions. Vesicles prefer to form in Ca surfactants with highly polar headgroups and C(n)DMAO with long chain length.
详细研究了钙表面活性剂（十二烷基硫酸钠（Ca(DS)(2)）、十二烷基磺酸钠（Ca(DSA)(2)）和月桂酸钙（CaL(2)）的亲水基团和烷基二甲基氧化胺（C(n)DMAO，n = 12、14、16）的疏水链对 Ca(2+)-配体配位囊泡形成的影响。在基于相行为研究的基础上，测量了流变性能和冷冻断裂透射电子显微镜（FF-TEM）图像。在不同的表面活性剂体系中观察到了非常不同的相行为。对于具有高极性基团的钙表面活性剂 Ca(DS)(2)，在所有 Ca(DS)(2)/C(n)DMAO（n = 12、14 和 16）体系中都观察到了囊泡，而对于具有较低极性基团的钙表面活性剂 Ca(DSA)(2)，在 Ca(DSA)(2)/C(n)DMAO 体系中 n = 14 和 16 可以形成囊泡，但 n = 12 不行。对于具有最小极性基团的钙表面活性剂 CaL(2)，只有在 CaL(2)/C(16)DMAO 体系中才能形成囊泡。结果表明，在由钙表面活性剂和 C(n)DMAO 形成的体系中，囊泡的形成不仅由 Ca(2+)与 C(n)DMAO 的 N → O 基团之间的相互作用驱动，还由静电和疏水相互作用驱动。囊泡更倾向于在具有高极性头基的钙表面活性剂和具有长链长度的 C(n)DMAO 中形成。
