School of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou, Jiangsu, PR China.
J Colloid Interface Sci. 2011 Aug 1;360(1):148-53. doi: 10.1016/j.jcis.2011.04.009. Epub 2011 Apr 16.
The self-assembly behavior of mixed systems consisting of amphiphilic chitosan derivatives C(n)-OCMCS (n=4, 6, 8) and the conventional cationic surfactant cetyltrimethylammonium bromide (CTAB) is investigated. Transmission electron microscopy (TEM), dynamic light scattering (DLS), small-angle X-ray diffraction (XRD), UV-vis spectra, and zeta potential measurements have been utilized to characterize the microstructures of C(n)-OCMCS/CTAB mixtures in aqueous solutions. Spherical vesicles are formed spontaneously in the C(n)-OCMCS (n=4, 6, 8)/CTAB mixed systems, and the increased hydrophobic chain length of C(n)-OCMCS enhances the ability to form vesicles. The addition of NaBr with higher concentrations to the vesicle system transforms vesicles into micelles, and an increase in temperature decreases the vesicle size. The results indicate that the main driving forces controlling vesicle formation may be attributed to the strong electrostatic interactions as well as the hydrophobic interactions, and also the hydrogen bonding between C(n)-OCMCS molecules.
由两亲性壳聚糖衍生物 C(n)-OCMCS（n=4、6、8）和常规阳离子表面活性剂十六烷基三甲基溴化铵（CTAB）组成的混合体系的自组装行为。透射电子显微镜（TEM）、动态光散射（DLS）、小角 X 射线衍射（XRD）、紫外可见光谱和zeta 电位测量用于表征水溶液中 C(n)-OCMCS/CTAB 混合物的微观结构。球形囊泡在 C(n)-OCMCS（n=4、6、8）/CTAB 混合体系中自发形成，并且 C(n)-OCMCS 的疏水性链长增加增强了形成囊泡的能力。向囊泡体系中加入更高浓度的 NaBr 将囊泡转化为胶束，升高温度会减小囊泡的尺寸。结果表明，控制囊泡形成的主要驱动力可能归因于强静电相互作用以及疏水相互作用，以及 C(n)-OCMCS 分子之间的氢键。
