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退变性腰椎侧凸中的根神经病:狭窄与选择性神经根类固醇注射缓解的相关性。

Radiculopathy in degenerative lumbar scoliosis: correlation of stenosis with relief from selective nerve root steroid injections.

机构信息

Division of Orthopaedics and Rehabilitation, Department of Surgery, Univerisity of Ioannina, Greece.

出版信息

Pain Med. 2011 Jan;12(1):45-50. doi: 10.1111/j.1526-4637.2010.01000.x. Epub 2010 Nov 18.

Abstract

OBJECTIVE

The purpose is to define the origin of radiculopathy of patients with degenerative lumbar scoliosis-stenosis and to assess the correlation between percentage of initial radicular leg pain relief with selective nerve root injections and lateral canal dimensions.

DESIGN

Retrospective clinical study.

SETTING AND PATIENTS

Thirty-six consecutive patients (average age 72) from Twin Cities Spine Center with degenerative lumbar scoliosis (average major curve 25°) and radicular symptoms were studied.

INTERVENTIONS

Patients underwent 46 selective steroid injections of nerve roots concordant with clinical symptomatology.

OUTCOME MEASURES

Radiographic measurements included major and lumbosacral curve Cobb angle. Computerized measurements of magnetic resonance imaging (MRI) included minimum subarticular height and foramen cross-sectional area of the nerve roots that were injected. Initial response from the nerve root injections was also rated.

RESULTS

Twenty-five percent of nerve root symptoms were coming from the major curve, 72.2% from the lumbosacral hemicurve and 2.8% from both (P<0.001). The affected nerve roots were more frequently the L4 (34.8%) and L5 (28.3%) nerve roots. A total of 71.7% of radicular symptoms were originating from the concavity of the curve and 28.7% from the convexity (P<0.001). The relief from injections was more than 50% in 75% of the patients at 15 days postinjection. There was no statistical significant correlation (P>0.05) between the lateral canal dimensions and the initial response to injection of anesthetic plus steroid injection.

CONCLUSIONS

In degenerative lumbar scoliotic curves, radicular symptoms are attributed mainly to nerve roots exiting from the concavity of the lumbosacral hemicurve. No evidence was found that the rate of initial relief from selective nerve root injections correlates with the degree of stenosis noted in the MRI.

摘要

目的

定义退行性腰椎侧凸-狭窄患者神经根病的起源,并评估选择性神经根注射初始神经根性腿痛缓解率与侧隐窝尺寸之间的相关性。

设计

回顾性临床研究。

地点和患者

从双城脊柱中心选择 36 例连续退行性腰椎侧凸患者(平均年龄 72 岁),并伴有神经根症状。

干预措施

患者接受了 46 例与临床症状相一致的神经根类固醇注射。

测量结果

放射学测量包括主要和腰骶角 Cobb 角。磁共振成像(MRI)的计算机测量包括注射神经根的最小关节突下高度和椎间孔横截面积。还对神经根注射的初始反应进行了评分。

结果

25%的神经根症状来自主曲线,72.2%来自腰骶半曲线,2.8%来自两者(P<0.001)。受影响的神经根更常是 L4(34.8%)和 L5(28.3%)神经根。71.7%的神经根症状来自曲线凹侧,28.7%来自凸侧(P<0.001)。75%的患者在注射后 15 天内注射麻醉加皮质类固醇的缓解率超过 50%。麻醉加皮质类固醇注射的初始反应与 MRI 显示的狭窄程度之间无统计学显著相关性(P>0.05)。

结论

在退行性腰椎侧凸曲中,神经根症状主要归因于从腰骶半曲线凹侧发出的神经根。没有证据表明选择性神经根注射初始缓解率与 MRI 中观察到的狭窄程度相关。

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