Kanna Rishi M, Shetty Ajoy P, Rajasekaran S
Ganga Hospital, Coimbatore, Tamil Nadu, India.
Global Spine J. 2019 Aug;9(5):473-479. doi: 10.1177/2192568218800050. Epub 2018 Sep 18.
Prospective, observational cohort study.
Selective nerve root block (SNRB) is an effective, standard interventional procedure for failed medical management in lumbar disc herniation (LDH). However, the factors that would predict successful outcomes in patients undergoing SNRB have not been clearly studied.
Patients with failed conservative treatment for acute LDH, treated with SNRB were periodically followed till 1 year. Patients who failed to have pain relief or had recurrent pain after SNRB, underwent surgery. The pattern of radiculogram during SNRB was classified into 4 types-"arm," "arrow," "linear," and "splash." Various clinical factors, radiological factors, and radiculograms were compared between patients who had consistent pain relief (group A) and those patients who did not (group B).
A total of 91 patients underwent SNRB. Sixty-nine had good pain relief maintained till 1 year (75.8% success). Twenty-two patients underwent surgery after failed NRB at a mean of 6.3 weeks. Patients with sensory symptoms ( = .01), higher mean preinjection Oswestry Disability Index (ODI) score ( = .02), higher mean postinjection ODI score at 3 weeks ( = .004), nonmanual job ( = .01), lumbosacral transitional segment ( = .00 005), and splash pattern of radiculogram ( = .005) were predictive of failed NRB. Logistic regression analysis showed that lumbosacral transitional segment at the level of LDH is the most significant factor predicting poor outcome.
SNRB is an effective technique to provide consistent symptom relief at least till 1 year in patients with acute LDH. The study identified several factors that predicted poor outcomes of SNRB and such patients can be forewarned about need for later surgery.
前瞻性观察队列研究。
选择性神经根阻滞(SNRB)是腰椎间盘突出症(LDH)保守治疗失败后的一种有效、标准的介入治疗方法。然而,对于接受SNRB治疗患者的成功预后预测因素尚未进行明确研究。
对急性LDH保守治疗失败且接受SNRB治疗的患者进行定期随访直至1年。SNRB后疼痛未缓解或复发的患者接受手术治疗。将SNRB期间神经根造影的模式分为4种类型——“臂型”、“箭头型”、“线型”和“喷射型”。比较疼痛持续缓解的患者(A组)和未持续缓解的患者(B组)之间的各种临床因素、放射学因素和神经根造影情况。
共有91例患者接受了SNRB。69例患者疼痛得到良好缓解并持续至1年(成功率75.8%)。22例患者在神经根阻滞失败后平均6.3周接受了手术。有感觉症状的患者(P = 0.01)、注射前平均Oswestry功能障碍指数(ODI)评分较高(P = 0.02)、3周时注射后平均ODI评分较高(P = 0.004)、非体力工作(P = 0.01)、腰骶移行节段(P = 0.00005)以及神经根造影的喷射型模式(P = 0.005)可预测神经根阻滞失败。逻辑回归分析表明,LDH水平的腰骶移行节段是预测预后不良的最显著因素。
SNRB是一种有效的技术,至少在1年内可为急性LDH患者持续缓解症状。该研究确定了几个预测SNRB预后不良的因素,可提前告知此类患者后续手术的必要性。