School of Chemistry and Chemical Engineering, Key Laboratory of Biotechnology for Medicinal Plant, Xuzhou Normal University, Xuzhou, Jiangsu 221116, PR China.
Bioorg Med Chem Lett. 2011 Jan 1;21(1):453-5. doi: 10.1016/j.bmcl.2010.10.127. Epub 2010 Oct 29.
A series of thieno[3,2-b]quinoline derivatives designed based on A-278637 scaffold, were synthesized efficiently via one-pot three-component reaction under solvent-free and catalyst-free conditions. This work provides a new compound library with potential biological activity for biomedical screening.
基于 A-278637 支架设计的一系列噻吩并[3,2-b]喹啉衍生物，通过无溶剂无催化剂条件下的一锅三步反应高效合成。这项工作为生物医学筛选提供了具有潜在生物活性的新化合物库。
