School of Chemistry and Chemical Engineering, Key Laboratory of Biotechnology for Medicinal Plant, Xuzhou Normal University, Xuzhou, Jiangsu 221116, PR China.
Bioorg Med Chem Lett. 2010 May 1;20(9):2884-7. doi: 10.1016/j.bmcl.2010.03.036. Epub 2010 Mar 11.
A series of novel 4-aryl-thiopyrano[3,4-b]pyran-5-one derivatives were synthesized through an efficient one-pot three-component reaction under solvent-free conditions. This work provides a new series of derivatives of thiorotenone with potential biological activity for biomedical screening.
通过无溶剂条件下的高效一锅法三组分反应,合成了一系列新型 4-芳基-噻吩并[3,4-b]吡喃-5-酮衍生物。这项工作为生物医学筛选提供了一系列具有潜在生物活性的硫瑞酮衍生物。