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芬兰中年人群中血糖紊乱及与生活方式相关的风险因素的社会经济差异。

Socio-economic differences in dysglycemia and lifestyle-related risk factors in the Finnish middle-aged population.

机构信息

Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland.

出版信息

Eur J Public Health. 2011 Dec;21(6):768-74. doi: 10.1093/eurpub/ckq164. Epub 2010 Nov 18.

Abstract

BACKGROUND

The aim of this study was to investigate the association of socio-economic status (SES) with dysglycemia and the lifestyle-related risk factors, and to analyze to which extent known risk factors explain socio-economic differences in diabetes risk.

METHODS

Two population-based cross-sectional surveys in Finland including 1696 men and 1946 women aged 45-64 years who participated in a health examination in 2004 or 2007. Dysglycemia was determined by an oral glucose tolerance test. Total type 2 diabetes (including previously known and screen-detected type 2 diabetes), impaired glucose tolerance and impaired fasting glucose formed the category of total dysglycemia. Questionnaires and clinical examination were completed to assess risk factors for dysglycemia. SES was defined by education and household income.

RESULTS

In both genders, the prevalence of total dysglycemia differed statistically significantly between educational groups. Low education was statistically significantly associated with higher risk of total type 2 diabetes in women. The household income level was inversely associated with total type 2 diabetes in women and with total dysglycemia in men. Obesity, unhealthy diet and smoking were all inversely related to SES in both men and women. The observed association between education and dysglycemia was slightly attenuated after adjustment for obesity and other risk factors for diabetes.

CONCLUSIONS

Low education was associated with an increased risk of dysglycemia more strongly than the low household income. Risk factors, especially obesity, explained only partly the observed associations between dysglycemia and education.

摘要

背景

本研究旨在探讨社会经济地位(SES)与糖代谢异常及生活方式相关危险因素之间的关系,并分析已知危险因素在多大程度上解释了糖尿病风险的社会经济差异。

方法

本研究纳入了芬兰两项基于人群的横断面研究,共纳入了 1696 名男性和 1946 名年龄在 45-64 岁之间的女性,他们在 2004 年或 2007 年参加了健康检查。糖代谢异常通过口服葡萄糖耐量试验确定。总 2 型糖尿病(包括已知和筛查出的 2 型糖尿病)、葡萄糖耐量受损和空腹血糖受损构成了总糖代谢异常的类别。通过问卷调查和临床检查评估了糖代谢异常的危险因素。SES 由教育程度和家庭收入定义。

结果

在两性中,不同教育程度组之间的总糖代谢异常患病率存在统计学差异。女性中,低教育程度与总 2 型糖尿病的风险升高显著相关。家庭收入水平与女性的总 2 型糖尿病和男性的总糖代谢异常呈负相关。肥胖、不健康饮食和吸烟在男性和女性中均与 SES 呈负相关。调整肥胖和其他糖尿病危险因素后,教育与糖代谢异常之间的观察到的关联略有减弱。

结论

与低家庭收入相比,低教育程度与糖代谢异常的风险增加更相关。危险因素,尤其是肥胖,仅部分解释了糖代谢异常与教育之间的观察到的关联。

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