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Genome-wide RNAi screen discovers functional coupling of alternative splicing and cell cycle control to apoptosis regulation.

作者信息

Wang Qingqing, Silver Pamela A

出版信息

Cell Cycle. 2010 Nov 15;9(22):4419-21. doi: 10.4161/cc.9.22.14051.

DOI:10.4161/cc.9.22.14051
PMID:21088477
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3142361/
Abstract
摘要

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本文引用的文献

1
An alternative splicing network links cell-cycle control to apoptosis.一种剪接调控网络将细胞周期控制与细胞凋亡联系起来。
Cell. 2010 Aug 20;142(4):625-36. doi: 10.1016/j.cell.2010.07.019. Epub 2010 Aug 12.
2
Cell cycle kinases as therapeutic targets for cancer.细胞周期激酶作为癌症的治疗靶点。
Nat Rev Drug Discov. 2009 Jul;8(7):547-66. doi: 10.1038/nrd2907.
3
The spliceosome: design principles of a dynamic RNP machine.剪接体:一种动态核糖核蛋白机器的设计原理
Cell. 2009 Feb 20;136(4):701-18. doi: 10.1016/j.cell.2009.02.009.
4
Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing.通过高通量测序对人类转录组中可变剪接复杂性进行深度研究。
Nat Genet. 2008 Dec;40(12):1413-5. doi: 10.1038/ng.259. Epub 2008 Nov 2.
5
Whole genome functional analysis identifies novel components required for mitotic spindle integrity in human cells.全基因组功能分析鉴定出人类细胞有丝分裂纺锤体完整性所需的新组分。
Genome Biol. 2008;9(2):R44. doi: 10.1186/gb-2008-9-2-r44. Epub 2008 Feb 26.
6
Global analysis of mRNA splicing.mRNA剪接的全局分析
RNA. 2008 Feb;14(2):197-203. doi: 10.1261/rna.868008. Epub 2007 Dec 14.
7
Splicing in disease: disruption of the splicing code and the decoding machinery.疾病中的剪接:剪接密码与解码机制的破坏
Nat Rev Genet. 2007 Oct;8(10):749-61. doi: 10.1038/nrg2164. Epub 2007 Aug 29.
8
RNA regulons: coordination of post-transcriptional events.RNA调节子:转录后事件的协调
Nat Rev Genet. 2007 Jul;8(7):533-43. doi: 10.1038/nrg2111.
9
Identification of pathways regulating cell size and cell-cycle progression by RNAi.通过RNA干扰鉴定调控细胞大小和细胞周期进程的信号通路
Nature. 2006 Feb 23;439(7079):1009-13. doi: 10.1038/nature04469.
10
Alternative splicing of Bcl-2-related genes: functional consequences and potential therapeutic applications.Bcl-2相关基因的可变剪接:功能后果及潜在治疗应用
Cell Mol Life Sci. 2004 Sep;61(17):2189-99. doi: 10.1007/s00018-004-4001-7.