Livanov G A, Batotsyrenov B V, Lodiagin A N, Batotsyrenova Kh V, Shestova G V
Klin Med (Mosk). 2010;88(5):55-8.
Examination and treatment of 66 patients severely intoxicated with neurotropic poisons showed that inclusion of reamberin in combined therapy decreased the degree of tissue hypoxia as apparent from increased oxygen consumption, oxygen utilization index, and arteriovenous oxygen difference. This in turn accelerated recovery of antioxidant protection and lowered activity of lipid peroxidation. The use of reamberin for the treatment of acute neurotropic intoxication improves clinical conditions of the patients by decreasing duration of the comatose state, requirement for intensive therapy, and lethality.
对66例严重神经毒性毒物中毒患者的检查和治疗表明，在联合治疗中加入雷姆布林可降低组织缺氧程度，这从耗氧量增加、氧利用指数和动静脉氧差增大可以明显看出。这反过来又加速了抗氧化保护的恢复，并降低了脂质过氧化活性。使用雷姆布林治疗急性神经毒性中毒可通过缩短昏迷状态持续时间、减少强化治疗需求和降低死亡率来改善患者的临床状况。
