Giroud O, Meier P, San Millán D, Praz G
Département de médecine, CHCVs-Sion.
Rev Med Suisse. 2010 Oct 13;6(266):1918-21.
In presence of immunosuppression Cytomegalovirus (CMV) infection can cause severe and potentially fatal infection involving multiple organs. In healthy immunocompetent individuals CMV usually causes an asymptomatic or mild infection with spontaneous cure. No specific therapy is needed. Rarely, however, the primary infection can be severe with multiple organs injuries and fatal cases are described. In these situations antiviral therapy is indicated and the clinical and biological response is very rapidly good. We describe a clinical case and present a review of the literature.
在免疫抑制情况下,巨细胞病毒(CMV)感染可导致累及多个器官的严重且可能致命的感染。在健康的免疫功能正常个体中,CMV通常引起无症状或轻度感染,可自愈,无需特殊治疗。然而,原发性感染很少会很严重,伴有多器官损伤,也有致命病例的报道。在这些情况下,需要进行抗病毒治疗,临床和生物学反应通常很快就会良好。我们描述了一个临床病例并对文献进行了综述。