Department of Neurology, Shengjing Hospital of China Medical University, Shenyang 110817, PR China.
Virol J. 2011 Mar 4;8:95. doi: 10.1186/1743-422X-8-95.
It is to describe an immunocompetent adult patient with hepatitis and Guillain-Barré syndrome (GBS) after Cytomegalovirus (CMV) infection. In the initial course of the diagnosis and treatment, CMV infection was ignored.
A 19-year-old Chinese girl complained of fatigue with pain and numbness of the limbs, with abnormal liver function. She was diagnosed as a case of GBS based on history, clinical findings and auxiliary examinations. On day 13 of admission, her liver function was still abnormal. So CMV was recommended to examine. CMV hepatitis was diagnosed on positive serum anti-CMV IgG and IgM antibodies. The case was improved only with intravenous immunoglobulin therapy, without the use of antiviral therapy.
This case showed an immunocompetent adult patient with hepatitis and GBS induced by CMV. The physicians should take into account multi-system involvement of severe CMV infection.
描述一例免疫功能正常的成人患者，其在巨细胞病毒（CMV）感染后发生肝炎和吉兰-巴雷综合征（GBS）。在最初的诊断和治疗过程中，忽略了 CMV 感染。
一名 19 岁的中国女孩主诉疲劳伴四肢疼痛和麻木，肝功能异常。根据病史、临床发现和辅助检查，诊断为 GBS 病例。入院第 13 天，她的肝功能仍异常。因此建议检查 CMV。阳性血清抗 CMV IgG 和 IgM 抗体诊断为 CMV 肝炎。该病例仅通过静脉注射免疫球蛋白治疗得到改善，未使用抗病毒治疗。
本例为一例免疫功能正常的成人患者，由 CMV 引起肝炎和 GBS。医生应考虑到严重 CMV 感染多系统受累的可能性。
