[接触化学品工人生物监测的分析质量：摩德纳工作场所预防与安全服务机构的经验]
[Analytical quality in biological monitoring of workers exposed to chemicals: experience of the Prevention and Safety at the Workplace Service in Modena].
作者信息
Alpaca R I Paredes, Migliore A, Di Rico R, Canali Claudia, Rota Cristina, Trenti T, Cariani Elisabetta
机构信息
Servizio Prevenzione e Sicurezza Ambienti di Lavoro, Area Sud, AUSL Modena.
出版信息
Med Lav. 2010 Jul-Aug;101(4):243-51.
BACKGROUND
The quality of laboratory data is one of the main factors in guaranteeing efficacy of biological monitoring.
OBJECTIVES
To analyze the quality of laboratory data used for biological monitoring of exposed workers.
METHODS
A survey involving 18 companies employing 945 workers in the area of Modena, Italy, was carried out in 2008.
RESULTS
Most of the 9 private laboratories receiving biological samples did not perform directly part or all of the laboratory assessments requested, but this was not indicated in the final report. Major problems were observed in the application of internal quality control, and only one laboratory participated in external quality assessment for blood lead measurements.
CONCLUSIONS
Our results raise major concerns on the traceability and reliability of laboratory assessments performed for biomonitoring of exposed workers. Systematic evaluation of the quality of analytical data would be highly recommendable.
背景
实验室数据质量是保证生物监测有效性的主要因素之一。
目的
分析用于接触工人生物监测的实验室数据质量。
方法
2008年，在意大利摩德纳地区对18家公司的945名工人进行了一项调查。
结果
接收生物样本的9家私人实验室中，大多数并未直接进行部分或全部要求的实验室评估，但最终报告中并未指出这一点。在内部质量控制的应用方面存在重大问题，只有一家实验室参与了血铅测量的外部质量评估。
结论
我们的结果引发了对接触工人生物监测所进行的实验室评估的可追溯性和可靠性的重大担忧。强烈建议对分析数据质量进行系统评估。
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