Department of Agroindustry, Food and Nutrition, Luiz de Queiroz College of Agriculture, University of São Paulo, Piracicaba, São Paulo, Brazil.
J Med Food. 2010 Dec;13(6):1355-62. doi: 10.1089/jmf.2009.0246.
Cardiovascular disease is a serious public health problem; it is the first "cause of death" in Brazil and in developed countries. Thus, it is essential to search for alternative sources such as some functional foods to prevent and control the risks of this disease. The purpose of this study was to evaluate the lipidemic parameters in hypercholesterolemic rats fed diets containing black rice variety IAC 600 or unrefined rice. Adult male Wistar rats (Rattus norvegicus var. albinos) were used, weighing about 200-220 g. The animals were divided into four groups: the first received a control casein diet, the second received hypercholesterolemic diet, and the other two groups, after induction of hypercholesterolemia, received the test diets, the first containing 20% black rice and the second 20% unrefined, for 30 days. It was observed that diet containing black rice reduced the level of plasma cholesterol, triglycerides, and low-density lipoprotein. For high-density lipoprotein values, the diet that provided an increase in the levels was the black rice. The diet containing black rice was more effective in controlling the lipidemia in rats compared with the whole rice diet.
心血管疾病是一个严重的公共卫生问题；它是巴西和发达国家的第一“死因”。因此，寻找替代来源，如一些功能性食品，以预防和控制这种疾病的风险是至关重要的。本研究的目的是评估高脂血症大鼠喂养含黑米品种 IAC 600 或糙米的饮食后的血脂参数。使用成年雄性 Wistar 大鼠（Rattus norvegicus var. albinos），体重约 200-220 克。将动物分为四组：第一组接受对照酪蛋白饮食，第二组接受高胆固醇饮食，另外两组在诱导高胆固醇血症后，分别接受含有 20%黑米和 20%糙米的试验饮食，共 30 天。结果表明，含黑米的饮食降低了血浆胆固醇、甘油三酯和低密度脂蛋白的水平。对于高密度脂蛋白值，提供升高水平的饮食是黑米。与全米饮食相比，含黑米的饮食更能有效控制大鼠的血脂异常。
