Department of Dermatology, Ise Municipal General Hospital, Ise, Mie, Japan.
Int J Dermatol. 2010 Dec;49(12):1403-5. doi: 10.1111/j.1365-4632.2010.04584.x.
An 81-year-old female experiencing high fever, fatigue, and loss of appetite was admitted to our hospital and diagnosed with acute cholecystitis. Her condition did not improve and an eschar and erythema subsequently appeared. We then diagnosed Japanese spotted fever (JSF). She recovered immediately after the administration of minocycline. This case differed from other cases because the patient had a remarkably acute hepatic failure.
Considering that the present case might be associated with other factors, we performed a repeat polymerase chain reaction (PCR) test on the patient's blood that had been collected on admission and stored.
Epstein-Barr virus (EBV) was detected in her blood by PCR.
We consider this case might be associated with EBV.
一位 81 岁女性患者因高热、乏力和食欲不振而入院，被诊断为急性胆囊炎。她的病情没有改善，随后出现了焦痂和红斑。我们随后诊断为日本斑点热（JSF）。给予米诺环素后，她立即康复。与其他病例不同的是，该患者的肝衰竭极为严重。
鉴于本病例可能与其他因素有关，我们对患者入院时采集并储存的血液进行了重复聚合酶链反应（PCR）检测。
PCR 检测到患者血液中的 EBV（Epstein-Barr virus）。
我们认为本病例可能与 EBV 有关。
