Allergy and Dermatology Center, Quito, Ecuador.
Int J Dermatol. 2010 Dec;49(12):1421-3. doi: 10.1111/j.1365-4632.2009.04430.x.
Hyperpigmented fixed eruption is a phenomenon usually related with drug antigens, and known as fixed drug eruption. A woman had a skin condition with clinical and histopathologic indications of fixed drug eruption. The disease first appeared when she went to a swimming pool and left with hyperpigmented macules. Previously affected skin reactivated on three other occasions when she again visited swimming pools. Sunlight involvement (UVA-UVB) was demonstrated through phototests. Sunlight should be considered as a cause of fixed drug-like eruption and a possible cause of some cases of FDE without any apparent etiological factor.
色素沉着固定性皮疹是一种通常与药物抗原相关的现象,也被称为固定性药疹。一名女性患有皮肤病,其临床表现和组织病理学均提示为固定性药疹。她第一次发病是在去游泳池游泳后,出现了色素沉着性斑疹。随后,当她再次去游泳池时,三次其他部位的原有皮损也相继出现。光试验显示,光照(UVA-UVB)参与了发病过程。固定性药疹样皮疹的发病原因可能是日光(UVA-UVB),而某些无明显病因的 FDE 也可能是由其引起。