Department of Urology, Singapore General Hospital, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Int J Urol. 2010 Dec;17(12):974-9. doi: 10.1111/j.1442-2042.2010.02668.x.
Benign prostate enlargement (BPE) is a common disease affecting elderly men. It can present clinically in many ways including, but not exclusively, lower urinary tract symptoms (LUTS) and acute urinary retention (AUR). Therefore, in managing men with BPE, a correct diagnosis in the outpatient setting is important. Diagnosis of BPE in the clinic can be aided by simple, non-invasive, transabdominal ultrasound (TAUS). In our practice, a normal prostate is generally defined as less than 20 mL, and shows no intravesical prostatic protrusion (IPP) to distort the normal funneling bladder neck on TAUS, with a maximum flow rate of more than 15 mL/s. The degree of IPP can be measured non-invasively in the midsagittal plane, and can be graded accordingly. Studies have shown that the grade of IPP correlates well with the degree of bladder outlet obstruction (BOO). In addition, TAUS can also be used to measure prostate volume (PV) and post-void residual urine (PVR). There is a good correlation between IPP and PV, but IPP is a better predictor for BOO. Patients with low-grade IPP, no significant PVR (<100 mL) and no bothersome symptoms (low stage) can generally be watched; whereas those with high-grade IPP, significant PVR (>100 mL) and bothersome symptoms (higher stage) will need more aggressive management. The final decision for management can then be tailored and individualized to achieve cost-effectiveness.
良性前列腺增生(BPE)是一种常见的老年男性疾病。它可以通过多种方式表现出来,包括但不限于下尿路症状(LUTS)和急性尿潴留(AUR)。因此,在管理 BPE 患者时,在门诊进行正确的诊断非常重要。在临床中,通过简单、无创的经腹超声(TAUS)可以辅助诊断 BPE。在我们的实践中,通常将正常前列腺定义为小于 20 毫升,并且在 TAUS 上没有导致正常漏斗状膀胱颈变形的膀胱内前列腺突出(IPP),最大尿流率大于 15 毫升/秒。IPP 的程度可以在正中矢状面进行无创测量,并相应分级。研究表明,IPP 程度与膀胱出口梗阻(BOO)程度密切相关。此外,TAUS 还可用于测量前列腺体积(PV)和剩余尿量(PVR)。IPP 与 PV 之间存在良好的相关性,但 IPP 是 BOO 的更好预测指标。IPP 程度低、PVR 不显著(<100 毫升)且症状不明显(低分期)的患者一般可以观察;而 IPP 程度高、PVR 显著(>100 毫升)且症状明显(高分期)的患者则需要更积极的管理。然后,可以根据患者的具体情况制定和个体化管理方案,以实现成本效益。