Department of Nephrology and Hypertension, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Nephrology (Carlton). 2010 Dec;15(8):732-9. doi: 10.1111/j.1440-1797.2010.01428.x.
Randomized controlled trials are the ideal study design to evaluate the effectiveness of health-care interventions. The conduct of a clinical trial is a collaborative effort between participants, investigators and a range of health-care professionals involved both centrally and locally in the coordination and execution of the trial. In this article, the key steps that are required to design a randomized controlled trial are summarized.
随机对照试验是评估医疗干预措施有效性的理想研究设计。临床试验的进行是参与者、研究者和一系列在中央和地方参与试验协调和执行的医疗保健专业人员之间的协作努力。本文总结了设计随机对照试验所需的关键步骤。